Safety and Feasibility of Laparoscopic Nephrectomy for Big Tumors (≥ 10 cm): A Retrospective Multicentric Study

Verhoest, G.; Couapel, J.-P.; Oger, Emmanuel; Rioux‐Leclercq, Nathalie; Pignot, G.; Patard, Jean‐Jacques; Bex, Axel; Panayotopoulos, P.; Bigot, Pierre; Eret, Viktor; Hora, Milan; Turna, Burak; Lefevre, Maxime; Rigaud, J.; Tillou, X.; Doerfler, A.; Xylinas, Évanguelos; Soorojebally, Yanish; Rouprêt, Morgan; Lagabrielle, Samuel; Bernhard, Jean-Christophe; Long, Jean-Alexandre; Berger, J.; Ravier, E.; Paparel, P.; Salomon, Laurent; Rodríguez, Alejandro; Bensalah, Karim

doi:10.1016/j.clgc.2016.01.007

Cited by 15 publications

(3 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[ 35 ] Open nephrectomy remains the standard for treating patients with the following findings: large advanced-stage tumors and/or perinephric extension, lymphadenopathy, thrombus in the renal vein and vena cava inferior – frequently with the need of cooperation of urologist with cardiovascular surgeons. [ 36 37 ] The highest number of cases was performed by a minimally invasive approach and nephron-sparing surgeries in the fourth quartile of the study. [ 15 ]…”

Section: Discussionmentioning

confidence: 99%

Trends in the surgical management of renal cell carcinoma in a contemporary tertiary care setting

Junejo¹,

Alkhateeb²,

Alrumayyan³

et al. 2021

Urol Ann

View full text Add to dashboard Cite

Background: In the last three eras, the incidence of renal cell carcinoma (RCC) has increased, due to increased radiological studies. The expected 5-year survival rate has become better, associated with the identification of small size renal masses. However, this survival improvement may be secondary to improved surgical techniques and medical therapies for these malignancies. Objectives: The objective was to report the trends of clinical presentation, peri-operative, oncological outcomes, and surgical management trends for RCCs over the period. Methods: After Institutional Review Board approval, a retrospective study for adult patients was conducted, who presented with renal mass and were managed between 2008 and 2019. Variables, including demographics, perioperative and pathological outcomes analyzed using descriptive statistics for continuous variables reported as mean ± standard deviation and categorical variables values compared by Chi-square test. Survival Analysis calculated using the Kaplan-Meier method. The level of significance is set at P-value < 0.05. Results: A total of 588 patients underwent surgical treatment for kidney cancer from January 2008 to January 2019. 237 (40.30%) were females and 351 (59.69%) males. The clinical presentation was higher as an incidental diagnosis of 58.67%. 71.25% of patients were from outside Riyadh city. Pathology was mostly clear cell RCC 61.22% and grade 2 (57.48%). Tumor size, surgery time, and length of hospital stay showed a significant difference between the three periods (both P > 0.05). Robotic surgery performed more than open ( P < 0.0001). There was no significant difference in the survival time, when compared to patients by the regions and when compared by the primary tumors (Log-Rank P = 0.4821). Patients from the Riyadh region (median = 54.0) had a significantly higher recurrence time (Log-Rank P < 0.0001). Conclusion: There was a rising trend in the incidence of RCC associated with comorbidities and incidental diagnosis. In our study period we found increase in the trend of minimal invasive approach. The size of the tumor, blood loss and operative time decreases over the period of time. The Robotic assisted nephrectomy approach has become increased over the period of time duration in present study.

show abstract

Section: Discussionmentioning

confidence: 99%

Trends in the surgical management of renal cell carcinoma in a contemporary tertiary care setting

Junejo¹,

Alkhateeb²,

Alrumayyan³

et al. 2021

Urol Ann

View full text Add to dashboard Cite

show abstract

“…La plupart des séries de NTL concernent des tumeurs de faible volume T1-T2. Cependant la laparoscopie a été rapportée pour des tumeurs plus volumineuses (T2a, T3, > 10 cm) : elle est faisable avec possiblement des avantages en termes de morbidité par rapport à la voie ouverte [6][7][8].…”

Section: éTat Des Lieux Et Fréquence Des Complicationsunclassified

Les complications de la néphrectomie totale et de la néphrectomie partielle : quelles sont-elles, comment les prévenir et les prendre en charge ?

Bensalah

Pignot

Legeais³

et al. 2022

Progrès en Urologie

View full text Add to dashboard Cite

“…The incidence of RCC is on the rise, however, its etiology is still poorly understood. At present, the main surgical approaches of RCC are radical nephrectomy and partial nephrectomy, and there are still greater risks of recurrence and metastasis after surgery [ 3 – 5 ]. Therefore, it is necessary to further explore the mechanisms underlying the occurrence and development of RCC.…”

Section: Introductionmentioning

confidence: 99%

Characterization of renal artery variation in patients with clear cell renal cell carcinoma and the predictive value of accessory renal artery in pathological grading of renal cell carcinoma: a retrospective and observational study

Zhou

Cui

et al. 2023

BMC Cancer

View full text Add to dashboard Cite

Objective To explore the characteristics of renal artery variation in patients with renal cell carcinoma and to evaluate the predicting value of accessory renal artery in the pathological grading of renal cell carcinoma. Methods The clinicopathological data of patients with clear cell renal cell carcinoma diagnosed in the Department of Urology of the First Hospital of Shanxi Medical University from September 2019 to March 2023 were retrospectively analyzed. All patients underwent visual three-dimensional model reconstruction from computed tomography images. All kidneys were divided into two groups: the affected kidney and the healthy kidney, and the incidence of renal artery variation in the two groups was analyzed. Then, according to the existence of accessory renal artery in the affected kidney, the patients were divided into two groups, and the relationship between accessory renal artery and clinicopathological features of patients with clear cell renal cell carcinoma was analyzed. Finally, univariate and multivariate logistic regression analyses were performed to determine the predictors of Fuhrman grading of clear cell renal cell carcinoma, and the predictive ability of the model was evaluated by the receiver operating characteristic curve. Results The incidence of renal artery variation and accessory renal artery in the affected kidney was significantly higher than them in the healthy kidney. The patients with accessory renal artery in the affected kidney had larger tumor maximum diameter, higher Fuhrman grade and more exophytic growth. The presence of accessory renal artery on the affected kidney and the maximum diameter of tumor are independent predictors of high-grade renal cell carcinoma. The receiver operating characteristic curve suggests that the model has a good predictive ability. Conclusion The existence of accessory renal artery on the affected kidney may be related to the occurrence and development of clear cell renal cell carcinoma, and can better predict Fuhrman grade of clear cell renal cell carcinoma. The finding provides a reference for the future diagnostic evaluation of RCC, and provides a new direction for the study of the pathogenesis of RCC.

show abstract

Safety and Feasibility of Laparoscopic Nephrectomy for Big Tumors (≥ 10 cm): A Retrospective Multicentric Study

Abstract: Laparoscopic nephrectomy for tumors > 10 cm can be performed safely. Complication rate and positive surgical margins are similar to open surgery. In experienced hands, the benefit of a mini invasive surgery remains evident.

Cited by 15 publications

References 15 publications

Trends in the surgical management of renal cell carcinoma in a contemporary tertiary care setting

Trends in the surgical management of renal cell carcinoma in a contemporary tertiary care setting

Les complications de la néphrectomie totale et de la néphrectomie partielle : quelles sont-elles, comment les prévenir et les prendre en charge ?

Characterization of renal artery variation in patients with clear cell renal cell carcinoma and the predictive value of accessory renal artery in pathological grading of renal cell carcinoma: a retrospective and observational study

Contact Info

Product

Resources

About