Safety profile after long-term administration of sildenafil to hyperlipidemic albino rats

El-Mahmoudy, Abubakr; Elgerwi, A.

doi:10.1016/j.vascn.2014.03.044

Cited by 1 publication

(1 citation statement)

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“…This finding was supported by Elkatcha et al, (41) who reported that there is no significant changes were observed in serum VLDL of broiler chickens supplemented with Saccharomyces cerevisiae. Also, similar results were observed by El-Mahmoudy et al (66) administration of Saccharomyces cerevisiae wall not alter serum cholesterol, triglycerides, HDL, LDL and VLDL in rats.…”

Section: Efficacy Of T-nil Plus® and Synertox® On Chickensupporting

confidence: 89%

Pharmacological effect of T-NilPlus® and Synertox®, commercial anti-mycotoxins, on broiler chickens in Egypt

et al. 2022

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The present study was carried out to investigate the potential ameliorative effect of two commercial anti-mycotoxins, containing Saccharomyces cerevisiae cell wall as prebiotic (T-Nil Plus®) and Bacillus subtilis as probiotic (Synertox®) on performance and some biochemical parameters of broilers. One hundred and twenty chicks one day old chicks were divided into 3 equal groups. 1st group was served as control, 2nd group was given T-Nil Plus®. The 3rd group was given Synertox®. Chicken’s performance was estimated. Serum samples obtained from each group for biochemical analysis. Tissues samples were collected for histopathological examination. The obtained results revealed that, T-Nil plus® induced a marked reduction in body weight gain and an elevation in Feed consumption, moreover, a marked elevation in, alanine aminotransferase (ALT), creatinine and malondialdehyde (MDA) and a marked reduction in aspartate aminotransferase (AST) was detected. While Synertox® caused a significant decrease in body weight, body weight gain and no change in feed conversion rate (FCR) and a marked elevation in ALT, creatinine and a marked reduction in AST and nitric oxide (NO) and it caused a significant reduction in serum glucose level of the birds. In conclusion, Synertox® induced a powerful effect comparing to T-Nil Plus®, as it induces a good FCR and increases the response of the birds against oxidative stress.

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Section: Efficacy Of T-nil Plus® and Synertox® On Chickensupporting

confidence: 89%