Safety standards for occupational exposure to dichloromethane

Skrabalak, Dale S.; Babish, John G.

doi:10.1016/0273-2300(83)90038-7

Cited by 8 publications

(3 citation statements)

References 19 publications

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“…However, dichloromethane could be toxic to humans [22] . On the other hand, ethanol was found to be a less toxic [23] and cheaper solvent that also provided a high antiacne property.…”

Section: Discussionmentioning

confidence: 99%

Anti-Acne-Inducing Bacterial Activity of Mangosteen Fruit Rind Extracts

Pothitirat

Chomnawang²,

Gritsanapan³

2010

Med Princ Pract

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Objective: The aims of this study were to determine the most effective solvent extract of mangosteen, anti-acne- inducing bacterial activity and the amount of α-mangostin, a major active component in each mangosteen fruit rind extract, using high-performance liquid chromatography (HPLC). Materials and Methods: The fruit rinds of mangosteen were extracted with hexane, dichloromethane, ethanol and water. The extracts were tested for antibacterial activity against bacteria that induce acne, including Propionibacterium acnes and Staphylococcus epidermidis. Thin-layer chromatographic autobiography against these bacteria was also performed for each extract, while the α-mangostin content was analyzed using a validated HPLC method. Results: The dichloromethane extract exhibited the strongest antibacterial effect with minimum inhibitory concentration values for both bacterial species at 3.91 µg/ml, while the minimum bactericidal concentration values against P. acnes and S. epidermidis were 3.91 and 15.63 µg/ml, respectively. Thin-layer chromatographic autobiography indicated that α-mangostin was present in all extracts, except the water extract, and is a major active component against both P. acnes and S. epidermidis. Using HPLC, the dichloromethane extract yielded the highest content (46.21% w/w) of α-mangostin followed by the ethanol extract (18.03% w/w), the hexane extract (17.21% w/w) and the water extract (0.54% w/w). Conclusions: Dichloromethane extract exhibited the strongest anti-acne-inducing bacterial effect and this extract yielded the highest amount of α-mangostin.

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“…However, dichloromethane could be toxic to humans [22] . On the other hand, ethanol was found to be a less toxic [23] and cheaper solvent that also provided a high antiacne property.…”

Section: Discussionmentioning

confidence: 99%

Anti-Acne-Inducing Bacterial Activity of Mangosteen Fruit Rind Extracts

Pothitirat

Chomnawang²,

Gritsanapan³

2010

Med Princ Pract

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“… 17–20 As per the safety standards for occupational exposure to dichloromethane (DCM), the concentration of DCM at TWA-75 ppm and a ceiling of 500 ppm was recommended using related functional departments. 21 Therefore, the precise detection of DCM is very desirable and important in the related industries. Currently, DCM gas sensors based on semiconductors, 22–25 carbon nanotubes, and polymers 26,27 have been reported.…”

Section: Introductionmentioning

confidence: 99%

Nanoporous fluorescent sensor based on upconversion nanoparticles for the detection of dichloromethane with high sensitivity

Wang

Zhan

et al. 2021

RSC Adv.

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“…A MIOSH medical officer administered a standardized questionnaire either in person or by telephone to two current and ten fonner R-W painters. The questionnaire requested information about (1) current and previous occupations, (2) time spent painting while at R-W, (3) other chemical exposures that might have causP.d neurological illness, (4) work hygiene and use of personal protective equipment, (5) smoking and alcohol consumotion, (6) neurologi cal history, and (7) qeneral health history.…”

Section: B Mec1 Icalmentioning

confidence: 99%

Health hazard evaluation report: HETA-83-113-1470, Raygo-Wagner, Portland, Oregon.

1983

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Safety standards for occupational exposure to dichloromethane

Cited by 8 publications

References 19 publications

Anti-Acne-Inducing Bacterial Activity of Mangosteen Fruit Rind Extracts

Anti-Acne-Inducing Bacterial Activity of Mangosteen Fruit Rind Extracts

Nanoporous fluorescent sensor based on upconversion nanoparticles for the detection of dichloromethane with high sensitivity

Health hazard evaluation report: HETA-83-113-1470, Raygo-Wagner, Portland, Oregon.

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