Salt-induced changes in the growth of polyelectrolyte layers of poly(diallyl-dimethylammonium chloride) and poly(4-styrene sulfonate of sodium)

Guzmán, Eduardo; Ritacco, Hernán; Rubio, J. E.; Rubio, Ramón G.; Ortega, Francisco

doi:10.1039/b901193e

Cited by 181 publications

(334 citation statements)

References 68 publications

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“…In order to charge the gold electrode of the quartz crystal, a self-assembled monolayer of sodium salt of 3-mercapto propanesulfonic acid was initially built onto the gold electrode, the surfaces modified in this way present a z-potential value of À42 mV. 19 D-QCM provided the impedance spectra of the crystal for the fundamental mode, and for odd overtones of the fundamental resonance up to the 11th central frequency (f 11 = 55 MHz). For the analysis of the data, we adopted the model proposed by Johannsmann et al 20 that provides the total adsorbed mass (polymer and water) and the shear compliance of the adsorbed layer.…”

Section: Techniquesmentioning

confidence: 99%

Influence of the molecular architecture on the adsorption onto solid surfaces: comb-like polymers

Guzmán

Ortega

Prolongo

et al. 2011

Phys. Chem. Chem. Phys.

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Section: Techniquesmentioning

confidence: 99%

Influence of the molecular architecture on the adsorption onto solid surfaces: comb-like polymers

Guzmán

Ortega

Prolongo

et al. 2011

Phys. Chem. Chem. Phys.

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“…In order to charge the gold electrode of the quartz crystal, a self-assembled monolayer of the sodium salt of 3-mercaptopropanesulfonic acid was initially built. 34 D-QCM provided the impedance spectra of the crystal for the fundamental mode and for odd overtones of the fundamental resonance up to the 11th (central frequency f 11 = 55 MHz). We adopted the model of Johannsmann et al 52 to relate the change of the quartz sensor impedance spectra with the adsorbed mass, m*, and the shear modulus of the adsorbed film,Ĵ,…”

Section: Techniques a Dissipative Quartz-crystal Microbalancementioning

confidence: 99%

“…ucm.es. Several variables have a strong influence in polyelectrolyte multilayers building process: charge density of the polymer, 29,30 polymer concentration, 31 ionic strength, [32][33][34] solvent quality for the polyelectrolytes, 33 pH, 35 and temperature 36 are the most relevant. A quantitative understanding of their effect on the structure of the multilayers is crucial, in part because multilayers are nonequilibrium systems, and therefore their structures also depend strongly on the conditions and procedures used for their growth.…”

mentioning

confidence: 99%

“…Silicon wafers (Siltronix, France) were used as the substrates. 34 The ellipsometric angles Δ and Ψ describe the changes in the state of polarization when the light is reflected at a surface. 56 These angles are related to the ratio of the Fresnel reflection coefficients for the parallel, r p , and perpendicular, r s , light-wave components with respect to the plane of incidence 56 by…”

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Polyelectrolyte Multilayers Containing Triblock Copolymers of Different Charge Ratio

et al. 2010

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Multilayers formed by the sodium salt of poly(4-styrenesulfonate), PSS, and triblock copolymers of the form PDMAEMA-PCL-PDMAEMA (PDMAEMA corresponding to poly [2-(N,N-dimethylamino)ethyl methacrylate), and PCL to poly(ε-caprolactone) have been built by layer-by-layer self-assembly from the aqueous polyelectrolyte solutions. Two types of block copolymers have been used which differ on the type of the amino groups, either hydrochloride or quaternized. This leads to changes in the charge density of the chains for the same content of amino groups. The growth of the multilayers has been followed using dissipative quartz crystal microbalance and ellipsometry techniques. The results show that, independently of the conditions used in the assembling, the film thickness grows linearly with the number of layers. The comparison of the thickness values obtained from D-QCM and ellipsometry has allowed us to calculate the water content of the polymer film. The analysis of the D-QCM data also provides the shear modulus, whose values are typical of a rubber-like polymer system. The analysis of the mass adsorbed calculated by the ellipsometric measurements indicated that the nature of the charge compensation mechanism is extrinsic for all the studied systems, although the degree of extrinsic compensation is strongly dependent on the copolymer used and the concentration in solution. Finally, it was found that the adsorption kinetic of the layers is bimodal for all the films built. Even though the characteristic adsorption times depend on the specific copolymer used, no dependence on the number of layers has been found for a given multilayer.

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“…Among the various surface engineering methods, the layer-by-layer assembly, refined by Decher in the 1990s [17], can be diversely used to tailor substrate properties and is particularly suitable to address material -cell interactions [18,19]. For example, different deposition parameters of the polyelectrolyte multilayers (PEMs), such as the type of polyelectrolytes [20,21], temperature [22], pH [23] and salt concentrations [24,25], have great impacts on hydration, swelling and mobility of the polymer chains. Consequently, the chemical composition, stability, surface functional groups, thickness, stiffness, hydration degree and surface roughness are varied, which in turn show different performance in terms of cell adhesion, proliferation and differentiation [23,[26][27][28].…”

Section: Introductionmentioning

confidence: 99%

Influences of surface chemistry and swelling of salt-treated polyelectrolyte multilayers on migration of smooth muscle cells

Han

Mao

et al. 2012

J. R. Soc. Interface.

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The cell migration plays a crucial role in a variety of physiological and pathological processes and can be regulated by the cell -substrate interactions. We found previously that the poly (sodium 4-styrenesulphonate) (PSS)/poly(diallyldimethylammonium) chloride (PDADMAC) multilayers post-treated in 1-5 M NaCl solutions result in continuous changes of their physicochemical properties such as thickness, chemical composition, surface charge, swelling ratio and wettability. In this study, the responses of human smooth muscle cells (SMCs) on these salt-treated multilayers, particularly the governing factors of cellular migration that offer principles for designing therapeutics and implants, were disclosed. The cell migration rate was slowest on the 3 M NaCl-treated multilayers, which was comparable with that on tissue culture plates, but it was highest on 5 M NaCl-treated multilayers. To elucidate the intrinsic mechanisms, cell adhesion, proliferation, adhesion and related gene expressions were further investigated. The SMCs preferred to attach, spread and proliferate on the PSS-dominated surfaces with well-organized focal adhesion and actin fibres, especially on the 3 M NaCl-treated multilayers, while were kept round and showed low viability on the PDADMAC-dominated surfaces. The relative mRNA expression levels of adhesion-related genes such as fibronectin, laminin and focal adhesion kinase, and migration-related genes such as myosin IIA and Cdc42 were compared to explain the different cellular behaviours. These results reveal that the surface chemistry and the swelling of the salt-treated multilayers govern the cell migration behaviours.

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Salt-induced changes in the growth of polyelectrolyte layers of poly(diallyl-dimethylammonium chloride) and poly(4-styrene sulfonate of sodium)

Cited by 181 publications

References 68 publications

Influence of the molecular architecture on the adsorption onto solid surfaces: comb-like polymers

Influence of the molecular architecture on the adsorption onto solid surfaces: comb-like polymers

Polyelectrolyte Multilayers Containing Triblock Copolymers of Different Charge Ratio

Influences of surface chemistry and swelling of salt-treated polyelectrolyte multilayers on migration of smooth muscle cells

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