Samba II PCR testing for COVID-19 in pregnant women: a retrospective cohort study and literature review

Xu, Ruiling; Pauley, Tara; Missfelder-Lobos, Hannah; Haddon, Richard; Gupta, Ravindra; Chong, Hsu Phern

doi:10.1186/s12884-021-03653-4

Cited by 4 publications

(4 citation statements)

References 30 publications

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“…La atención a la gestante implica en primer lugar, la identificación de portadores asintomáticos, lo cual promovería cambios en la vía de atención para prevenir infecciones nosocomiales, reduciendo el riesgo de transmisión asintomática a otras mujeres embarazadas y también a los trabajadores sanitarios (Gonzales-de la Torre et al, 2021;Xu et al, 2021). La prevención de infección en las gestantes es importante porque se debe tomar en cuenta que, si bien el riesgo de hacer enfermedad grave en las gestantes es similar o mayor al riesgo de los no gestantes (Merchan, Cedeño y Rayo, 2020), las probabilidades de que pueda necesitar UCI o asistencia para respirar son mayores (Centros para el Control y la Prevención de Enfermedades, 2019; Ellington et al, 2020;Peyronnet et al, 2020;Dubey et al, 2021).…”

Section: Atención a Gestantesunclassified

“…Los signos y síntomas que aparecen en las gestantes, son similares a los de no gestantes en algunos casos siendo ingresadas solo por fiebre, esto encuentra respaldo en lo reportado por Tsatsaris et al (2020); y, Xu et al (2021). Los casos de tipo leve presentaron ligeros síntomas clínicos y ausencia de cambios pulmonares en las imágenes de TC; en otro grupo de estudios se desconoce el curso de la enfermedad porque se reporta como asintomáticas y en aquellas que no requieren hospitalización.…”

Section: Sintomatologíaunclassified

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Vigilancia epidemiológica y atención a gestantes con Covid-19 en el sistema de salud

Mujica¹,

Espinoza²,

Vega³

2022

RCS

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gestante con Covid-19 en el sistema de salud a partir de una revisión sistemática. La metodología utilizada refiere a una revisión sistemática, enfoque cualitativo descriptivo. En los estudios analizados se tuvo un total de 1.009 gestantes con resultados 100% positivos al Sars-Cov 2 mediante prueba de PCR, de las cuales solo el 7,23% recibieron control prenatal, se halló transmisión vertical en 1,39% seguido de complicaciones obstétricas en su mayoría como la Preeclampsia, HTA gestacional, diabetes gestacional y parto pre-términos; hubo predominio de las cesáreas al 37%. La transmisión vertical ocurrió en solo 28 de un total de 1.009 RN, cuyo nexo epidemiológico se asocia al contacto directo de la madre. Se concluye que la vigilancia epidemiológica fue insuficiente a las gestantes con Covid-19; la tasa de mortalidad no fue mayor a la estimada para las no gestantes; y no hay transmisión vertical.

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Section: Atención a Gestantesunclassified

Section: Sintomatologíaunclassified

Vigilancia epidemiológica y atención a gestantes con Covid-19 en el sistema de salud

Mujica¹,

Espinoza²,

Vega³

2022

RCS

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“…The prevalence figures for SARS-CoV-2 in screened pregnant women vary in different publications, sometimes considerably (< 1 – 15%), which is largely due to the different prevalence in the general population (for example, New York City and London versus Thuringia in Germany) 28 , 30 , 42 , 43 , 44 , 45 , 46 . However, it is assumed that the “real” prevalence of infections is significantly higher, as up to 89% of infections are asymptomatic or mild 17 , 28 , 29 , 47 , 48 , 49 , 50 , 51 , 52 .…”

Section: Discussionmentioning

confidence: 99%

Prevalence of SARS-CoV-2 in Pregnant Women Assessed by RT-PCR in Franconia, Germany: First Results of the SCENARIO Study (SARS-CoV-2 prEvalence in pregNAncy and at biRth In FrancOnia)

Hein

Kehl

Häberle

et al. 2022

Geburtshilfe Frauenheilkd

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Purpose Detection of SARS-CoV-2-infected pregnant women admitted to maternity units during a pandemic is crucial. In addition to the fact that pregnancy is a risk factor for severe COVID-19 and that medical surveillance has to be adjusted in infected women and their offspring, knowledge about infection status can provide the opportunity to protect other patients and healthcare workers against virus transmission. The aim of this prospective observational study was to determine the prevalence of SARS-CoV-2 infection among pregnant women in the hospital setting. Material and Methods All eligible pregnant women admitted to the nine participating hospitals in Franconia, Germany, from 2 June 2020 to 24 January 2021 were included. COVID-19-related symptoms, secondary diseases and pregnancy abnormalities were documented. SARS-CoV-2 RNA was detected by RT-PCR from nasopharyngeal swabs. The prevalence of acute SARS-CoV-2 infection was estimated by correcting the positive rate using the Rogan–Gladen method. The risk of infection for healthcare workers during delivery was estimated using a risk calculator. Results Of 2414 recruited pregnant women, six were newly diagnosed RT-PCR positive for SARS-CoV-2, which yielded a prevalence of SARS-CoV-2 infection of 0.26% (95% CI, 0.10 – 0.57%). Combining active room ventilation and wearing FFP2 masks showed an estimated reduction of risk of infection for healthcare workers in the delivery room to < 1%. Conclusions The prevalence of newly diagnosed SARS-CoV-2 infection during pregnancy in this study is low. Nevertheless, a systematic screening in maternity units during pandemic situations is important to adjust hygienic and medical management. An adequate hygienic setting can minimise the calculated infection risk for medical healthcare workers during patientsʼ labour.

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“…Data obtained from systematic screening during birth revealed that approximately 14% of positive SARS-CoV-2 women are asymptomatic [8]. In 2020 also reported that the infection rate was 13.7% in the asymptomatic group and 87.9% of infected pregnant women had no symptoms of SARS-CoV-2 [9] in the UK. Whereas, among 215 who underwent prenatal screening in New York, 15% were positive, while approximately 87% had no symptoms.…”

Section: Introductionmentioning

confidence: 99%

Relationship of Vaccination History and Pregnancy Health Protocol Compliance with Positive Antigen Test Result at Community Health Center in Medan, Indonesia

Lumbanraja

Hayati

Sukatendel

et al. 2023

Open Access Maced J Med Sci

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BACKGROUND: A comprehensive screening at delivery revealed that roughly 14% of pregnant women who tested positive for COVID-19 did not exhibit any symptoms. The SARS-CoV-2 antigen swab test is frequently utilized as a diagnostic technique. Inadequate implementation of health protocol compliance can enhance the vulnerability of a community to the COVID-19 virus, according to previous findings. This suggests that these health protocol compliance and the vaccination program are important for preventing and controlling the spread of the virus. AIM: This study aims to determine the relationship of vaccination history and health protocol compliance with positive antigen swab results among pregnant women at the Community Health Center in Medan. METHODS: This is a cross-sectional and observational study that was conducted in February 2022 at the Community Health Center in Medan, North Sumatra, Indonesia. Two hundred pregnant women who met the inclusion and exclusion criteria make up the sample population. Antigen sampling for SARS-CoV-2 was performed in the Pramita laboratory. Following the collection and processing of sample and antigen swab data, IBM SPSS® version was utilized to conduct statistical analysis. RESULTS: The result showed that four of the pregnant women were infected with COVID-19, and they accounted for 2% of the sample population. The health protocol carried out by pregnant women was not significantly related to the swab results. Therefore, vaccination history had no significant association with COVID-19 symptoms, but people who received vaccines had more negative swab test results compared to those who did not, where three out of four positive samples were unvaccinated. CONCLUSION: Based on the results, only 2% of pregnant women were infected with COVID-19 at the Community Health Centre in Medan, because this study was carried out when COVID-19 cases had decreased. The statistical analysis results showed that the history of vaccination was not significantly related to SARS-CoV-2 antigen swab results. However, there was a clinical tendency that vaccines can reduce the number of positive cases, where three out of four positive samples were not vaccinated.

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Samba II PCR testing for COVID-19 in pregnant women: a retrospective cohort study and literature review

Cited by 4 publications

References 30 publications

Vigilancia epidemiológica y atención a gestantes con Covid-19 en el sistema de salud

Vigilancia epidemiológica y atención a gestantes con Covid-19 en el sistema de salud

Prevalence of SARS-CoV-2 in Pregnant Women Assessed by RT-PCR in Franconia, Germany: First Results of the SCENARIO Study (SARS-CoV-2 prEvalence in pregNAncy and at biRth In FrancOnia)

Relationship of Vaccination History and Pregnancy Health Protocol Compliance with Positive Antigen Test Result at Community Health Center in Medan, Indonesia

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