Sarcoid reaction associated with basal cell carcinoma

Pirfenidone-Induced Sarcoid-Like Reaction

“…Most commonly, they are described as a result of cancer, antineoplastic therapy, or immunomodulatory therapy. [7][8][9][10] Sarcoidosis and IPF are distinct clinical entities that very rarely coexist in the same patient. 11 The natural history of IPF is progressive fibrosis with respiratory failure and death.…”

Basal cell carcinoma associated with non-neoplastic cutaneous conditions: a comprehensive review

“…He presented for evaluation of facial actinic keratoses. Most of the lesions resolved after four weeks of topical imiquimod; however, a lesion on his nose persisted [79].…”

“…The plaque contained tiny black papules and superficial telangiectasia. He had neither clinical features of rosacea nor systemic findings of sarcoidosis [79].…”

“…The cells in the granuloma were immunoreactive for CD123 (which the investigators attributed to the presence of imiquimod-induced plasmacytoid dendritic cells) and CD68 (macrophages); in addition, the granuloma was surrounded by CD3-positive T cells. Stains for fungal and mycobacterial organisms were negative [79]. Surgical removal of the residual tumor was performed.…”

“…Surgical removal of the residual tumor was performed. A local flap was used to cover the postoperative wound [79].…”