Sarcoma intimal de artéria pulmonar: um diagnóstico diferencial do tromboembolismo pulmonar crônico

Abstract

Intimal sarcoma of the pulmonary artery is a rare and potentially lethal tumor, the diagnosis of which is difficult and therefore frequently delayed. The clinical signs and symptoms are nonspecific, often mimicking chronic pulmonary thromboembolism (CPTE). We report the case of a 45-year-old male under treatment for CPTE associated with pulmonary arterial hypertension and chronic cor pulmonale. There was no response to treatment with anticoagulants and sildenafil. We emphasize the difficulties in diagnosing intimal sarcoma of the pulmonary artery, the need to investigate this neoplasm in the differential diagnosis of CPTE and the systematic use of criteria for the appropriate prescription of new medications for pulmonary artery hypertension.

Clinical Characteristics and Treatment Outcomes of Primary Pulmonary Artery Sarcoma in Korea

“…There have been few reports of the long-term results of PAS treatment, especially in Asia. Due to its nonspecific clinical manifestations, including dyspnea on exertion, chest pain and cough, PAS is easily misdiagnosed as a pulmonary vascular disease such as pulmonary thromboembolism (PE) ( 2 3 ). These types of misdiagnoses can delay proper treatment.…”

Cor Pulmonale Pós Covid-19 – Um Relato De Caso / Cor Pulmonale Post Covid-19 – A Case Report

“…Pode apresentar-se através de dispneia recorrente (tanto a pequenos esforços, quanto síncope), dor torácica, tosse, edema de ISSN: 2525-8761 Brazilian Journal of Development, Curitiba, v.7, n.2, p. 16556-16562 feb. 2021 membros inferiores, distensão abdominal, opressão torácica, hemoptise e taquicardia. (DORNAS, 2009).…”

Pulmonary artery sarcoma mimicking chronic pulmonary thromboembolism

“…In general, it affects the central pulmonary arteries, close to the pulmonary valve ( 7 ) , resulting in significant morbidity and high mortality rates ( 8 ) . There is no predilection for sex, occurring most commonly in the fifth decade of life ( 9 ) .…”

“…In general, symptoms are nonspecific with dyspnea, cough, hemoptysis, chest pain and weight loss ( 8 ) , progressing to pulmonary hypertension, right ventricular failure, and possibly chronic cor pulmonale ( 9 ) . Clinical and radiological findings are frequently similar to thromboembolic disease.…”