Sarcoma mieloide intraoral: forma poco común de debut de la leucemia aguda mieloide

Abstract

La leucemia aguda mieloide (LAM) es una neoplasia maligna con manifestaciones sistémicas, pudiendo presentar lesiones a nivel intraoral. Es el cáncer más frecuente en la infancia y

Oral manifestations of leukemia as part of early diagnosis

“…Among the oral MOLs in hard tissues, two cases corresponded to ALL, 20 , 31 two cases corresponded to AML, 19 , 32 one case corresponded to chronic lymphocytic leukemia 28 and one case corresponded to adult T-cell leukemia/lymphoma. 11 Dental mobility was the most common clinical condition when hard tissues were affected.…”

“… 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 The age ranged from 6 to 74 years and only 6 individuals (18.18%) were between 1.6 and 12 years old. 10 , 19 , 22 , 26 , 31 , 32 …”

“…Among the types of leukemia, oral manifestations were present principally in acute myeloid leukemia (24 individuals [72.72%]), 9 , 12 , 14 , 15 , 16 , 17 , 18 , 19 , 22 , 23 , 24 , 25 , 30 , 32 followed by acute lymphoid leukemia (6 individuals [18.18%]), 10 , 13 , 20 , 21 , 26 , 31 adult T-cell leukemia/lymphoma (2 individuals [6.06%]) and chronic lymphoid leukemia (1 individual [3.03%]).…”

“…Oral MOLs as the first clinical signs were more common in soft tissues (27 individuals [81.81%]) than those in hard tissues (6 individuals [18.18%]). 11 , 19 , 20 , 28 , 31 , 32 Figure 2 shows the different sites.…”

“…In soft tissues, the differential diagnoses were gingival enlargement during pregnancy, 25 , 35 gingival enlargement induced by drugs, 41 squamous cell carcinoma and deep fungal infection, 28 pericoronarite, 21 oral manifestation of HIV, 15 , 33 postoperative complications of extraction, 14 , 36 candidiasis, 27 necrotizing acute gingivitis, 40 dental cyst eruption 32 and herpetic gingivostomatitis. 34 In addition, when the oral manifestation was in the maxillary bones, the presumptive diagnoses were acute osteomyelitis, 20 osteosarcoma 19 , 20 and Ewing sarcoma.…”