“…They obtained pyrrolidines 6 by heating 2‐(3‐aminoalkyl)furans 5 with HCl in the presence of H 2 and a hydrogenation catalyst (Scheme ) 9. The best yields of 6 were obtained with Pd/C9c or Ru‐promoted nickel;9d tetrahydrofurans 7 were important side‐products when the reaction was performed in the presence of Raney Co or Ni.…”
Section: Furan‐to‐azaheterocycle Transformations By Intramolecularmentioning
This review summarizes the results of recent investigations of intramolecular furan ring‐opening–azaheterocycle ring‐closing reactions induced by acid or electrophilic attack on the furan ring.
“…They obtained pyrrolidines 6 by heating 2‐(3‐aminoalkyl)furans 5 with HCl in the presence of H 2 and a hydrogenation catalyst (Scheme ) 9. The best yields of 6 were obtained with Pd/C9c or Ru‐promoted nickel;9d tetrahydrofurans 7 were important side‐products when the reaction was performed in the presence of Raney Co or Ni.…”
Section: Furan‐to‐azaheterocycle Transformations By Intramolecularmentioning
This review summarizes the results of recent investigations of intramolecular furan ring‐opening–azaheterocycle ring‐closing reactions induced by acid or electrophilic attack on the furan ring.
“…The reactions were performed at a temperature of 100~ and a hydrogen pressure of 10 MPa in an alcohol solution of ammonia or methylamine in the presence of Raney nickel catalyst [4,5].…”
Section: IV Ix:r=hn=i;mentioning
confidence: 99%
“…The synthesis of 2-(2-furfuryl)eycloalkylamines I-IV was performed according to [4,5]. Aminonitriles XII, XIII and diamines XIV, XV were obtained as described elsewhere [6].…”
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