Sb-doped FeOCl nanozyme-based biosensor for highly sensitive colorimetric detection of glutathione

Chen, Jiaqi; Wu, Hongjiao; Li, Jun; Su, Yiqian; Li, Huiqin; Lin, Pengcheng; Chen, Ying; Xiao, Wei; Cao, Donglin

doi:10.1007/s00216-022-04503-8

Cited by 14 publications

(1 citation statement)

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“…The calorimetric detection of biomolecules such as glutathione (GSH) is made possible by nanozyme-assisted biosensors. These biosensors nanorods are formed by doping of antimony (Sb) on iron oxychloride via a calcination process . Moreover, several lipids and sugars, including cholesterol and glucose, may be oxidized by their respective oxidases to produce H 2 O 2 , making it possible to measure the molecules with ease.…”

Section: Nanozymes As Biosensorsmentioning

confidence: 99%

Recent Advancements in the Formulation of Nanomaterials-Based Nanozymes, Their Catalytic Activity, and Biomedical Applications

Singh,

Rai,

Tiwari

et al. 2023

ACS Appl. Bio Mater.

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Nanozymes are nanoparticles with intrinsic enzyme-mimicking properties that have become more prevalent because of their ability to outperform conventional enzymes by overcoming their drawbacks related to stability, cost, and storage. Nanozymes have the potential to manipulate active sites of natural enzymes, which is why they are considered promising candidates to function as enzyme mimetics. Several microscopy- and spectroscopy-based techniques have been used for the characterization of nanozymes. To date, a wide range of nanozymes, including catalase, oxidase, peroxidase, and superoxide dismutase, have been designed to effectively mimic natural enzymes. The activity of nanozymes can be controlled by regulating the structural and morphological aspects of the nanozymes. Nanozymes have multifaceted benefits, which is why they are exploited on a large scale for their application in the biomedical sector. The versatility of nanozymes aids in monitoring and treating cancer, other neurodegenerative diseases, and metabolic disorders. Due to the compelling advantages of nanozymes, significant research advancements have been made in this area. Although a wide range of nanozymes act as potent mimetics of natural enzymes, their activity and specificities are suboptimal, and there is still room for their diversification for analytical purposes. Designing diverse nanozyme systems that are sensitive to one or more substrates through specialized techniques has been the subject of an in-depth study. Hence, we believe that stimuli-responsive nanozymes may open avenues for diagnosis and treatment by fusing the catalytic activity and intrinsic nanomaterial properties of nanozyme systems.

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Section: Nanozymes As Biosensorsmentioning

confidence: 99%