Scaffold hopping approaches for the exploration of herbicidally active compounds inhibiting Acyl‐ACP Thioesterase
Tyler Fahrenhorst‐Jones,
Stephanie Lee,
Birgit Bollenbach‐Wahl
et al.
Abstract:BACKGROUNDThe sustainable control of weed populations is a significant challenge facing farmers around the world. Although various methods for the control of weeds exist, the use of small molecule herbicides remains the most effective and versatile approach. Striving to find novel herbicides that combat resistant weeds via the targeting of plant specific modes of action (MoAs), we further investigated the bicyclic class of acyl‐acyl carrier protein (ACP) thioesterase (FAT) inhibitors in an effort to find safe … Show more
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