Scandcleft randomized trials of primary surgery for unilateral cleft lip and palate: dental anomalies in 8-year olds

Abstract

Summary Background Children born with unilateral cleft lip and palate (UCLP) are reported to display several dental anomalies including agenesis, supernumeraries, as well as variations in dental size, shape, and path of eruption. The extensive sample of individuals with UCLP included in the Scandcleft randomized control trials offers the opportunity to study more rare conditions, which is seldom possible with limited samples. Objectives The aim was to study dental anomalies at 8 years of age in children born with UCLP included in the Scandcleft randomized control trials. Methods Panoramic and intraoral radiographs from 425 individuals (279 males and 146 females) with a mean age of 8.1 years were assessed by four orthodontists regarding dental anomalies. Results Agenesis was found in 52.5 per cent and supernumerary teeth in 16.9 per cent of the participants. The cleft lateral was missing in 43.8 per cent and was found peg shaped in 44.7 per cent. The distribution of ectopic eruption was 14.6 per cent, mainly affecting maxillary first molars, while transposition was found in 3.4 per cent of the individuals. In addition, infraocclusion of one or several primary molars was registered in 7.2 per cent of the participants. Conclusion We conclude that 8-year-old children born with UCLP display multiple dental anomalies. The Scandcleft sample allowed rarely studied conditions such as infraocclusion of primary molars and transposition to be studied in children born with UCLP. Trial registration ISRCTN29932826.

Anomalías dentarias de número, presentes en pacientes con labio y paladar fisurado, de 6 a 12 años de edad. Revisión de literatura.

“…La presencia de anomalías dentales en pacientes con LPF es bastante frecuente, pues está bien documentada en la literatura que los niños afectados por esta alteración son notablemente más predisponentes a manifestar diferentes anomalías dentales en comparación con la población en general. 13 Entre los diferentes tipos de anomalías dentales se encuentran: alteraciones de número, forma, tamaño, posición y erupción; las cuales afectan tanto a la dentición temporal como a la dentición permanente. 14 Dichas alteraciones se manifiestan tanto en el área de la fisura, como fuera de ella y además puede manifestarse en la mandibula.…”

“…14 Dichas alteraciones se manifiestan tanto en el área de la fisura, como fuera de ella y además puede manifestarse en la mandibula. 13 Según un estudio realizado por Rengifo R. en 2016 14 (Colombia) en una población de niños con Fisura Labio Palatina encontró que las anomalías más prevalentes fueron agenesia dental, mayor al 90% y dientes supernumerarios en un 40%.…”

“…Es así que dentro de las alteraciones dentales más comunes está la agenesia dental y dientes supernumerarios. según Rizell S. en 2019 13 "La agenesia se manifiesta en un 40% a 61% de los niños afectados con LPF"; y Navas M. en 2017 15 manifestó que "Los dientes supernumerarios, reportan una prevalencia en pacientes con labio y paladar hendido en un 28%".…”

Prevalência de dentes supranumerários em pacientes atendidos em uma clínica-escola de odontologia do norte do Rio Grande do Sul

“…Khandelwal et al (2018) observaram uma prevalência de 0,63% em sua pesquisa que encontrou 82 dentes extras em 58 indivíduos, resultado semelhante ao encontrado por Bandaru et al ( 2019), que relatou uma prevalência de 0,2%. Estes estudos encontraram uma baixa porcentagem em comparação com os 4,67% encontrados nesta pesquisa; já Rizell et al (2019), ao encontrar uma prevalência de 16,9%, discorda de todos os autores citados anteriormente.…”

Deep orofacial phenotyping of population-based infants with isolated cleft lip and isolated cleft palate

“…Dentitional anomalies, in terms of deviations in the number of teeth, malformation of teeth and delayed tooth maturation and eruption, have been reported to affect both the primary and the permanent dentitions, at or remote from the cleft site 17 , 20 , 21 , 32 , 33 . These characteristics may be integral in the spectrum of defects in non-syndromic OFC.…”