Scanning and transmission electron microscope studies of the supraependymal neurons in the third ventricular wall of the arctic lamprey,Lampetra japonica.

Chibá, Akira; Honma, Yoshio; Nakai, Yasumitsu; Shioda, Seiji

doi:10.1679/aohc1950.44.477

Cited by 7 publications

(2 citation statements)

References 19 publications

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“…The distribution of the CSF-contacting neurons in the hypothalamus of the lamprey (cf. CHIBA et al, 1981) is also similar to that of higher vertebrates. Our interest was focused on simpler organisms than cyclostomes in order to collect data on the phylogenetic origin of these peculiar elements in lower deuterostomians.…”

Section: Neuronssupporting

confidence: 63%

The system of cerebrospinal fluid-contacting neurons.

Vigh-Teichmann

Vígh

1983

Arch. Histol. Jap., Arch. Histol. Jpn

128

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Section: Neuronssupporting

confidence: 63%

The system of cerebrospinal fluid-contacting neurons.

Vigh-Teichmann

Vígh

1983

Arch. Histol. Jap., Arch. Histol. Jpn

128

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“…The core of the scar at 2 weeks had more cellular elements than at 10 weeks. The small sizes of the cells labeled by the neuronal marker in the core region (arrows in Figure 10E ) suggested that they were most likely CSF-contacting neurons that are located in the subependymal region surrounding the central canal in the intact SC (Chiba et al, 1981 ; Rodicio et al, 2008 ; Villar-Cervino et al, 2008 ; Zhang et al, 2014b ; Jalalvand et al, 2018 ). The non-neuronal (ependymal glia) cells were much less heavily labeled.…”

Section: Resultsmentioning

confidence: 99%

The Composition and Cellular Sources of CSPGs in the Glial Scar After Spinal Cord Injury in the Lamprey

Zhang

Jin

Rodemer

et al. 2022

Front. Mol. Neurosci.

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Axon regrowth after spinal cord injury (SCI) is inhibited by several types of inhibitory extracellular molecules in the central nervous system (CNS), including chondroitin sulfate proteoglycans (CSPGs), which also are components of perineuronal nets (PNNs). The axons of lampreys regenerate following SCI, even though their spinal cords contain CSPGs, and their neurons are enwrapped by PNNs. Previously, we showed that by 2 weeks after spinal cord transection in the lamprey, expression of CSPGs increased in the lesion site, and thereafter, decreased to pre-injury levels by 10 weeks. Enzymatic digestion of CSPGs in the lesion site with chondroitinase ABC (ChABC) enhanced axonal regeneration after SCI and reduced retrograde neuronal death. Lecticans (aggrecan, versican, neurocan, and brevican) are the major CSPG family in the CNS. Previously, we cloned a cDNA fragment that lies in the most conserved link-domain of the lamprey lecticans and found that lectican mRNAs are expressed widely in lamprey glia and neurons. Because of the lack of strict one-to-one orthology with the jawed vertebrate lecticans, the four lamprey lecticans were named simply A, B, C, and D. Using probes that distinguish these four lecticans, we now show that they all are expressed in glia and neurons but at different levels. Expression levels are relatively high in embryonic and early larval stages, gradually decrease, and are upregulated again in adults. Reductions of lecticans B and D are greater than those of A and C. Levels of mRNAs for lecticans B and D increased dramatically after SCI. Lectican D remained upregulated for at least 10 weeks. Multiple cells, including glia, neurons, ependymal cells and microglia/macrophages, expressed lectican mRNAs in the peripheral zone and lesion center after SCI. Thus, as in mammals, lamprey lecticans may be involved in axon guidance and neuroplasticity early in development. Moreover, neurons, glia, ependymal cells, and microglia/macrophages, are responsible for the increase in CSPGs during the formation of the glial scar after SCI.

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Scanning electron microscopy of central nervous system cerebrospinal-fluid-contacting surfaces: A bibliography (1963-1995)

Mitchell

Ham

1998

Microsc. Res. Tech.

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Scanning and transmission electron microscope studies of the supraependymal neurons in the third ventricular wall of the arctic lamprey,Lampetra japonica.

Cited by 7 publications

References 19 publications

The system of cerebrospinal fluid-contacting neurons.

The system of cerebrospinal fluid-contacting neurons.

The Composition and Cellular Sources of CSPGs in the Glial Scar After Spinal Cord Injury in the Lamprey

Scanning electron microscopy of central nervous system cerebrospinal-fluid-contacting surfaces: A bibliography (1963-1995)

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