Scanning Electron Microscopic Features of Nasolacrimal Silastic Stents Retained for Prolong Durations Following Dacryocystorhinostomy

Abstract

This is the first study to exclusively report on scanning electron microscopic features of lacrimal stents retained for long durations. Further studies on physical elements within the deposits and protein analysis would provide more insights into stent-tissue interactions.

<p>Bicanalicular Intubation with the Kaneka Lacriflow for Proximal Lacrimal Drainage System Stenosis</p>

“…16 For Crawford stents retained for greater than 1 year in patients lost to follow-up after DCR, biofilms were also noted to be more extensive with greater stent retention time. 17 However, in both of these studies, none of the patients showed clinical signs or symptoms of infection, and the clinical implications of the observed biofilms are not well understood. 16,17 The Lacriflow tube is made of a different polymer than Monoka and Crawford stents, which could hold different properties in relation to biofilm formation.…”

“…17 However, in both of these studies, none of the patients showed clinical signs or symptoms of infection, and the clinical implications of the observed biofilms are not well understood. 16,17 The Lacriflow tube is made of a different polymer than Monoka and Crawford stents, which could hold different properties in relation to biofilm formation. 6 Future studies are indicated comparing Lacriflow stents to other bicanalicular systems in the rates of clinically evident colonization as well as biofilm formation.…”

“…9 This may be corroborated by scanning electron microscopy, which reveals biofilm formation on nasolacrimal stents. 16,17 Biofilms have been noted to form on Monoka stents as early as 6 weeks after stent placement and are more extensive with longer stent retention time. 16 For Crawford stents retained for greater than 1 year in patients lost to follow-up after DCR, biofilms were also noted to be more extensive with greater stent retention time.…”

Mitomycin C after endoscopic endonasal dacryocystorhinostomy

“…Авторы вышеописанной методики проводят антифибротическую профилактику только в тканях полости носа, не воздействуя при этом на ткани слезного мешка. Кроме того, в конце операции они интубируют дакриостому силиконовым имплантатом, что сопряжено не только с нежелательной продолжительной его ретенцией, но и с возможным развитием ряда осложнений, в частности с образованием грануляций и инфицированием (в том числе устойчивыми возбудителями, ассоциированными с биопленками [27]), что может привести к рецидиву дакриоцистита [28].…”

Microbiology and Biofilm Trends of Silicone Lacrimal Implants: Comparing Infected Versus Routinely Removed Stents

“…The same group recently published scanning electron microscopic imaging data demonstrating the presence of biofilm on silastic stents after routine and prolonged duration stent removal following DCR. 11,12 Questions remain regarding the primary pathogens responsible for infection, whether organisms growing on clinically infected lacrimal stents are the same as those found in normal nasolacrimal flora, and the role of biofilm in pathogenesis.…”