Scanning laser edema index: A reliable tool to correlate with diabetic retinopathy and systemic risk factors?

Peyman, Mohammadreza; Iqbal, Tajunisah; Loo, Angela; Chuah, Khai Choon; Subrayan, Visvaraja

doi:10.1016/j.jdiacomp.2012.03.019

Cited by 3 publications

(1 citation statement)

References 19 publications

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“…Regarding the examination techniques, Brown et al and Browning et al suggested that OCT is superior to contact lens biomicroscopy for detecting DME, especially in mild cases [19, 20]. Various systemic factors have been associated with increased incidences of DME, such as duration of diabetes [21], levels of albuminuria [15, 21], cholesterol [15, 22], serum creatinine [21], uncontrolled renal parameters, hypertension [15, 23], and aging and genetic defects [24, 25]. Our study confirmed that elevated blood glucose and systolic pressure made significant contributions to DME.…”

Section: Discussionmentioning

confidence: 99%

The Status of Maculopathy in Diabetes and Prediabetes Patients in a Population-Based Study Detected by Optical Coherence Tomography: The 2011 Health Examination Survey in Beijing

Cao

Zhong

et al. 2017

BioMed Research International

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Objective The aim of the study was to investigate the prevalence and the risk factors of maculopathy detected by optical coherence tomography (OCT) in a Chinese population with diabetes or prediabetes. Methods. 8,155 people were randomly selected to participate in the 2011 annual Health Examination Survey in Beijing. A 75 g oral glucose tolerance test (OGTT) was tested in 3760 subjects with fasting plasma glucose (FPG) ≥ 5.6 mmol/L. Of 3,760 subjects, 583 were also randomly selected to take OCT. Results In this study population, 21 (3.95%) patients had maculopathy. Eight patients had diabetes macular edema (DME) and the prevalence was 6.72% in diabetes patients and 1.51% in all subjects. Eleven patients had age-related macular degeneration (AMD) and the prevalence was 3.36% in diabetes patients and 2.07% in all subjects. Logistic regression model confirmed that elevated HbA1c (p < 0.001) and systolic pressure (p < 0.05) made significant contributions to DME. Stepwise regression analysis revealed that HbA1c and blood creatinine were significantly independent influence factors for central subfield thickness (CST) (p = 0.01, p < 0.001). Conclusions High prevalence of maculopathy was found in patients with diabetes in a Chinese population. Maculopathy poses a significant public health problem in China with rapid rising trend of diabetes.

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Section: Discussionmentioning

confidence: 99%

The Status of Maculopathy in Diabetes and Prediabetes Patients in a Population-Based Study Detected by Optical Coherence Tomography: The 2011 Health Examination Survey in Beijing

Cao

Zhong

et al. 2017

BioMed Research International

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Correlation of morphological pattern of optical coherence tomography in diabetic macular edema with systemic risk factors in middle aged males

Ghosh¹,

Bansal²,

Shejao³

et al. 2014

Int Ophthalmol

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To study correlation of different optical coherence tomography (OCT) patterns of diabetic macular edema (DME) with systemic risk factors. Institutional cross-sectional double-masked non-interventional study with 330 eyes of middle-aged male type 2 diabetes patients with DME. Various systemic parameters were measured. Diffuse retinal thickening (DRT), cystoid and serous patterns of DME were identified on OCT. Comparison between DRT versus non-DRT and serous versus non-serous eyes was done in respect to systemic parameters. Correlation of serous and DRT pattern was tested with systemic parameters above and below specified values. Mean age was 54.4 ± 7.1 years. Mean duration of diabetes was 8.7 ± 4.2 years. Mean serum globulin level was significantly higher (p = 0.018) in serous compared to non-serous group. Prevalence of serous DME was significantly high in those with serum globulin level >3.5 gm/dl (prevalence ratio = 3.01, p = 0.040). Significant correlation of central macular thickness was observed with duration of diabetes (p = 0.002, r = 0.440).Visual acuity (logMAR) was correlated significantly with HbA1C (p = 0.031, r = 0.305). Increased serum globulin, a positive phase reactant of inflammation, was found significant independent risk factor for development of serous DME. This study did not identify any modifiable systemic factor for any of the OCT patterns in DME.

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Association of urinary albumin excretion with central foveal thickness and intravitreal conbercept treatment frequency in patients with diabetic macular edema

Liu¹

2019

Int J Ophthalmol

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Scanning laser edema index: A reliable tool to correlate with diabetic retinopathy and systemic risk factors?

Cited by 3 publications

References 19 publications

The Status of Maculopathy in Diabetes and Prediabetes Patients in a Population-Based Study Detected by Optical Coherence Tomography: The 2011 Health Examination Survey in Beijing

The Status of Maculopathy in Diabetes and Prediabetes Patients in a Population-Based Study Detected by Optical Coherence Tomography: The 2011 Health Examination Survey in Beijing

Correlation of morphological pattern of optical coherence tomography in diabetic macular edema with systemic risk factors in middle aged males

Association of urinary albumin excretion with central foveal thickness and intravitreal conbercept treatment frequency in patients with diabetic macular edema

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