Schiff Bases and Their Metallic Derivatives: Highly Versatile Molecules with Biological and Abiological Perspective

Abstract

1998 onwards, a span reporting thousands of research articles describes the ever-increasing applicability of Schiff bases and their metallic complexes; this chapter comprehensively examines the literature of the last 20 years. The structural diversity of these molecules made them available for a very wide range of biological and abiological applications. Schiff bases are excellent chelators and due to this unique property have found their place in qualitative and quantitative determination of metals in aqueous media. The structural diversity of metal chelates proved these to be outstanding catalysts and displayed interesting fluorescence effect. Finally, Schiff base moieties have found a unique position during the in vitro and in vivo experiments for drug development against a huge number of biological entities including bacteria, fungi, cancer cells, viruses, parasites, etc.

Synthesis And Characterization ( Oxazepine , Thiazine and Quinazoline ) Derivatives And Study The Biological Activity As Antibacterial

“…1 FT-IR spectrum data for the compound (5) show peak at3322cm -1 for (OH), 3255cm -1 for (Ar -H) , 2923cm -1 for (C-H) in CH3 ,1656cm -1 for (C=O), 1608 cm -1 for (C=N), 1434 cm -1 for (C=C),1226 cm -1 for (C-S). 1 HMNR spectrum data of compound ( 5 FT-IR spectrum data for the compound (7) show peak at 3440cm -1 for (OH) 3078cm -1 for (Ar -H) , 2923cm -1 for (C-H) in CH3 , 1650cm -1 for (C=O), 1564cm -1 for (C=C),1253 cm -1 for (C-S). 1 HMNR spectrum data of compound (7) The results show that derivetives reduce significant antibacterial effectiveness.…”

“…1 HMNR spectrum data of compound ( 5 FT-IR spectrum data for the compound (7) show peak at 3440cm -1 for (OH) 3078cm -1 for (Ar -H) , 2923cm -1 for (C-H) in CH3 , 1650cm -1 for (C=O), 1564cm -1 for (C=C),1253 cm -1 for (C-S). 1 HMNR spectrum data of compound (7) The results show that derivetives reduce significant antibacterial effectiveness. against show good . "…”

“…, and compound that staphylococcus aurous against ( . activity are (1,2,3,4,5,6,7) ) , the results of the antibacterial activity staphylococcus aurous against ( good activity are (2) are shown in the fig ( 22…”

“…Schiff's bases are defined as the products of the chemical reaction of a primary amine with an aldehyde or a ketone under a given set of structural conditions. or azimethine (((C= N) with liberated water molecule which is a feature of schiff bases (7) . Is the chief bases is very important as it plays an important role in various fields such as chemistry of inorganic, organic, biological, agricultural and analytical terms are used with some metal ions as pesticides, fungi, manufacture of dyes, corrosion inhibitors and is also characterized by the biological effectiveness of high as anti-cancer (8,9) .…”

Synthesis and Characterization of Tetradentate Schiff Base Ligand Containing 3,4-Diamino Benzophenone and Investigation of Complex Formation with Ni (II), Cu (II) and Co (II) metal ions

“…Metal complexes obtained from Schiff bases are among the molecules with the most comprehensive study area due to their easy synthesis [9]. Some complexes of Schiff bases, which have applications in clinical and analytical fields, are molecules that model oxygen transport systems in biological activities [10]. It is known that complexes formed from tetradentate Schiff bases form stable complex structures with the N2O2 donor system [7,11].…”