Scientific Evidence Between The Use of Oral Contraceptives And Thrombotic Events: An Integrative Review

Abstract

Introduction: Women with chronic diseases are at higher risk of worsening their clinical condition, with the possibility of developing thrombotic events, when they make prolonged use of hormonal oral contraceptives.Objective: To identify in the literature the scientific evidence on thrombotic events resulting from the use of oral contraceptives by women. Material and Method:Integrative literature review, using the databases of the Virtual Health Library and the Journal of the Coordination for the Improvement of Higher Education Personnel as a research source, using the search terms "contraceptives" and "hormonal contraceptives" and "peripheral venous thrombosis". With this search, 156 publications were initially found, after making the selection, 13 scientific articles were included in the review. The texts were submitted to semantic content analysis.Results: Two categories were highlighted, which were discussed concurrently: the use of oral contraceptives: clinical and theoretical aspects; association between the use of oral contraceptives and thrombotic events. Conclusion:Thrombotic events occur in most women who make long-term use of hormonal oral contraceptives, especially those whose composition is estrogen. It will help professionals to adequately guide women in choosing the contraceptive method, considering the complications.