Scintillator screen for measuring low-dose halo in scanning carbon-ion therapy

Yogo, Katsunori; Tatsuno, Yuya; Souda, Hikaru; Matsumura, Akihiko; Tsuneda, Masato; Hirano, Yoshiyuki; Ishiyama, Hiromichi; Saito, A.; Ozawa, Shogo; Nagata, Yasushi; Nakano, Takashi; Hayakawa, Kazushige; Kanai, Tatsuaki

doi:10.1016/j.radmeas.2020.106299

Cited by 4 publications

(3 citation statements)

References 35 publications

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“…The FWHM for the data measured with the scintillator agreed to within 1.5 mm with those obtained using the chamber ( Figs 7 and 8 ). This agreement of the ZnS profile with the chamber profiles is consistent with previous data for the pencil beam [ 20 , 21 ].…”

Section: Discussionsupporting

confidence: 91%

“…We previously reported that the ZnS scintillator provided a lower LET dependence on carbon ions than Gd-based scintillators [ 20 ]. Thus, ZnS scintillators require much smaller corrections than Gd scintillators in estimating dose distributions based on brightness distributions for carbon-ion pencil beams [ 20 , 21 ].…”

Section: Discussionmentioning

confidence: 99%

“…A silver-activated zinc sulfide (ZnS) scintillator was selected for carbon-ion beam dosimetry with a higher LET [ 17–19 ]. In a previous study, we proposed a ZnS scintillator for measuring dose profiles in high- and low-dose regions of carbon-ion pencil beams [ 20 , 21 ]. This technique proved to be superior to methods employing a Gd-based scintillator in terms of LET.…”

Section: Introductionmentioning

confidence: 99%

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Three-dimensional dose-distribution measurement of therapeutic carbon-ion beams using a ZnS scintillator sheet

Yogo

Tsuneda

Horita

et al. 2021

Journal of Radiation Research

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The accurate measurement of the 3D dose distribution of carbon-ion beams is essential for safe carbon-ion therapy. Although ionization chambers scanned in a water tank or air are conventionally used for this purpose, these measurement methods are time-consuming. We thus developed a rapid 3D dose-measurement tool that employs a silver-activated zinc sulfide (ZnS) scintillator with lower linear energy transfer (LET) dependence than gadolinium-based (Gd) scintillators; this tool enables the measurement of carbon-ion beams with small corrections. A ZnS scintillator sheet was placed vertical to the beam axis and installed in a shaded box. Scintillation images produced by incident carbon-ions were reflected with a mirror and captured with a charge-coupled device (CCD) camera. A 290 MeV/nucleon mono-energetic beam and spread-out Bragg peak (SOBP) carbon-ion passive beams were delivered at the Gunma University Heavy Ion Medical Center. A water tank was installed above the scintillator with the water level remotely adjusted to the measurement depth. Images were recorded at various water depths and stacked in the depth direction to create 3D scintillation images. Depth and lateral profiles were analyzed from the images. The ZnS-scintillator-measured depth profile agreed with the depth dose measured using an ionization chamber, outperforming the conventional Gd-based scintillator. Measurements were realized with smaller corrections for a carbon-ion beam with a higher LET than a proton. Lateral profiles at the entrance and the Bragg peak depths could be measured with this tool. The proposed method would make it possible to rapidly perform 3D dose-distribution measurements of carbon-ion beams with smaller quenching corrections.

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Section: Discussionsupporting

confidence: 91%