Scleroderma and interstitial lung disease - A case report

Gul, Fahad; Siddiqui, Amna; Srikaram, Prakhyath; Fatima, Nabeela

doi:10.1016/j.amsu.2022.104143

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2024

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“…It is a connective tissue disease with an unclear aetiology, varying clinical symptoms, a chronic course that frequently progresses, and a tendency to include many organs, including the lungs. About 80% of patients with SSc develop lung fibrosis, and 25% go on to develop progressive interstitial lung disease (ILD), which has a 40% 10-year death rate and is one of the main causes of morbidity and mortality [4].…”

Section: Introductionmentioning

confidence: 99%

Scleroderma Associated With Organising Pneumonia and Polyarthritis: A Report of a Rare Case

Reddy,

Ghewade,

Jadhav

et al. 2024

Cureus

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Cryptogenic organising pneumonia (COP) is a form of idiopathic diffuse interstitial lung disease (ILD) that develops in response to a variety of unknown irritants. An essential component of the development of organising pneumonia (OP) is damage to type II pneumocytes and the alveolar basement membrane. An autoimmune illness called systemic sclerosis (SSc) has a significant death rate from cardiopulmonary involvement such as pulmonary hypertension and ILD. Arthritis is an autoimmune disorder, in which the patients experience extra-articular symptoms such as ILD during the course of their disease, and COP frequently coexists with these conditions. It is exceedingly uncommon for OP to occur as the initial sign of arthritis, and its clinical characteristics are still unclear. Scleroderma and inflammatory polyarthritis related to COP are presented in this report.

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Section: Introductionmentioning

confidence: 99%