Sclerosing Microcystic Adenocarcinoma Arising from the Tongue: A Case Report and Literature Review

Abstract

Sclerosing microcystic adenocarcinoma is a rare and recently characterized cancer that affects the mucosal surfaces of the head and neck without adnexal involvement. Histologically, microcystic adnexal carcinoma of the skin resembles it. It does, however, contain unique characteristics that merit our attention for potential diagnostic errors. Therefore, we present a 48-year-old male with sclerosing microcystic adenocarcinoma of the tongue, along with a full discussion and a brief review of pertinent literature.

Magnetic resonance imaging findings of sclerosing microcystic adenocarcinoma: A case report and review of the literature

“… [17] 67 F Right parotid gland MRI Excision and adjuvant radiotherapy Disease free (6) 21 Lee et al. [18] 48 M Tongue FDG-PET/CT Excision Disease free (30) 22 Present case 61 F Floor of mouth MRI Excision and adjuvant radiotherapy Disease free (21) …”

“…To our knowledge, no study has conducted a detailed review of the MRI findings of SMA. Among the 21 reported cases of SMA, imaging findings were described in 4, as follows: computed tomography (CT) (n = 2), 18F-fluorodeoxyglucose-positron emission tomography/CT (18F-FDG-PET/CT) (n = 1), and MRI (n = 2) [ 11 , 13 , 17 , 18 ]. As these reports did not describe the imaging findings of the SMA in detail, we reviewed the available images and summarized the findings as follows.…”

“…As these reports did not describe the imaging findings of the SMA in detail, we reviewed the available images and summarized the findings as follows. On CT, the SMA had ill-defined borders and showed isodensity with the surrounding muscle [ 13 , 18 ]. The lesion showed high uptake of FDG on 18F-FDG-PET/CT (standardized uptake value not stated) [18] .…”

“…On CT, the SMA had ill-defined borders and showed isodensity with the surrounding muscle [ 13 , 18 ]. The lesion showed high uptake of FDG on 18F-FDG-PET/CT (standardized uptake value not stated) [18] . MRI findings revealed an iso-signal intensity to muscle on T2WI with gadolinium enhancement [ 11 , 17 ].…”

“…proposed the term “sclerosing microcystic adenocarcinoma (SMA)” for a rare malignant tumor occurring in the salivary glands, closely resembling cutaneous MAC [11] . To our knowledge, 21 cases of SMA have been reported, but none have evaluated the magnetic resonance imaging (MRI) findings of SMA in detail [4] , [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] . Here, we report an additional case of SMA of the floor of the mouth and discuss its MRI findings.…”