Sclerosing Orbital Inflammation and Systemic Disease

Winn, Bryan J.; Rootman, Jack

doi:10.1097/iop.0b013e31823d2103

Cited by 15 publications

(3 citation statements)

References 62 publications

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“…Visual acuity was impaired in cases of optic nerve or posterior sclera involvement. Sometimes, systemic symptoms, such as leukocytosis and fever, might indicate inflammation, which was consistent with observations made by other authors [3,21,22,25,27,40].…”

Section: A B C Dsupporting

confidence: 91%

“…Orbital pseudotumors are idiopathic inflammatory processes occurring within the orbit and involving hypertrophy of fibrovascular tissue with low cellular polymorphism and lymphoplasmacytic infiltrations. Usually, orbital pseudotumors do not extend beyond the borders of the orbit, and their clinical course may be very diverse [21,22,25,40]. A total of 17 patients diagnosed with pseudotumors were selected from the population of non-malignant orbital lesion patients and subjected to diagnostic examinations for IgG4-related disease.…”

Section: A B C Dmentioning

confidence: 99%

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Original article IgG4-related inflammatory orbital pseudotumors – a retrospective case series

Oleś¹,

Szczepański²,

Składzień³

et al. 2015

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Orbital diseases may be divided into congenital defects of the orbit, infectious and inflammatory diseases, orbital tumors (including malignant and benign tumors) and injuries. Idiopathic inflammatory syndromes are often encountered within the orbit and are usually classified as orbital pseudotumors. The etiology of pseudotumors of the vision organ is unknown. Infectious agents, autoimmune disorders and improper healing are taken into consideration in the pathogenesis of this disorder. Thanks to detailed studies conducted in recent years, a new disease syndrome was identified in 2001. It is known as IgG4-related disease, and its differentiation is based on the analysis of IgG4 levels in the affected tissues. Orbital locations of the disease were first reported in Japan as late as at the end of 2009. This finding triggered the European studies on this subject. To date, no such studies have been conducted in Poland. The starting study population consisted of 167 patients with isolated infiltrative tumor diseases within the orbital region treated at the

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Section: A B C Dsupporting

confidence: 91%

Section: A B C Dmentioning

confidence: 99%

Original article IgG4-related inflammatory orbital pseudotumors – a retrospective case series

Oleś¹,

Szczepański²,

Składzień³

et al. 2015

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“…12,13 Mickulicz disease was first characterized in 1888 and for some decades was conflated with Sjögren syndrome. 12,13 Mickulicz disease was first characterized in 1888 and for some decades was conflated with Sjögren syndrome.…”

Section: "Other" Diseases Subsumed By Igg4-rdmentioning

confidence: 99%