Scoring Systems and Risk Stratification in Cirrhotic Patients with Acute Variceal Bleeding "Scoring in Variceal Bleeding"

Mohammad, Ahmad M.; Morsy, Khairy Hammam

doi:10.4172/2167-0889.1000195

Cited by 3 publications

(4 citation statements)

References 25 publications

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“…Scoring that can predict poor outcomes in variceal bleeding, which is a disease-specific condition associated with upper gastrointestinal bleeding and cirrhosis, is focused on the prognosis of liver disease, as predicted by the MELD or Child–Pugh scores [ 2 ]. Existing upper gastrointestinal bleeding (UGIB) scores require various laboratory data and physical examination findings, such as history, ascites through ultrasonography, cardiac function evaluation, endoscopic findings, and dynamic blood pressure changes, heart rate, and level of consciousness [ 3 ].…”

Section: Discussionmentioning

confidence: 99%

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Usefulness of the d-dimer to albumin ratio for risk assessment in patients with acute variceal bleeding at the emergency department: retrospective observational study

et al. 2022

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Background Acute variceal bleeding (AVB) is a severe complication of portal hypertension that is caused by rupture of the esophageal or gastric varix. Scoring system for risk stratification of AVB is difficult to use because various variables must be entered, and it is difficult to apply early in the emergency department (ED). We compared and analyzed the usefulness of the D-dimer to albumin ratio (DAR) for risk stratification of AVB. Methods In this retrospective observational study, medical records of patients with AVB Between January 2019 and December 2020 were assessed. The primary endpoint was to evaluate whether DAR was a predictor of clinical outcomes for AVB. Receiver operating characteristic (ROC) curves were constructed using cut-off values determined by the Youden Index. Univariate and multivariate logistic regression analyses were performed to assess the factors contributing to the development of outcomes. Results Overall, 67 patients required intensive care. The cut-off value of DAR for patients requiring intensive care was 400. A DAR > 400 (adjusted HR: 5.636 [95% CI: 2.216–14.332]) independently predicted the need for ICU admission in these patients. Overall, 13 patients required long-term hospitalization. The cut-off value of DAR for patients requiring long-term hospitalization was 403. A DAR > 403 (adjusted HR: 9.899 [95% CI: 2.012–48.694]) independently predicted the need for long-term hospitalization. Overall, 95 patients required transfusion. The cut-off value of DAR for patients requiring transfusion was 121. A DAR > 121 (adjusted HR: 4.680 [95% CI: 1.703–12.862]) independently predicted the need for transfusion. Overall, 11 patients died during study period. The cut-off value of DAR for mortality was 450. A DAR > 450 (adjusted HR: 26.261 [95% CI: 3.054–225.827]) independently predicted mortality. Conclusions The DAR can be used for outcome assessment in patients with AVB with various scoring systems, but its explanatory power is not high.

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Section: Discussionmentioning

confidence: 99%

“…Acute variceal bleeding (AVB) is a severe complication of portal hypertension that is caused by rupture of the esophageal or gastric varix [ 1 ]. The prognosis of patients with AVB is associated with liver-disease severity [ 2 ]. The Child–Pugh and model end-stage liver disease (MELD) scores have been traditionally used [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Usefulness of the d-dimer to albumin ratio for risk assessment in patients with acute variceal bleeding at the emergency department: retrospective observational study

et al. 2022

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“…Although AIMS65 score was not significantly different from MELD, SOFA, and APACHEII scores, it was the best among them in prediction of mortality. 16…”

Section: In a Retrospective Study Done By Sung Min Park Et Al That Inmentioning

confidence: 99%

A Comparative Study of AIMS 65 Score with other Scoring Systems to Predict Outcomes in Patients with Upper GI Bleed in Chronic Liver Disease

Bs¹,

Madhumathi²,

Chidananda.³

et al. 2019

IJCMR

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Introduction:The AIMS 65 score is a new bedside score proposed for the assessment of liver function which is simple and more independent. Different scores have been recommended to predict outcomes in the setting of upper gastrointestinal bleeding (UGIB), limited comparative studies have been published between simplified versions of older scores and recent scores. In this present study, we aimed to retrospectively compare the performance of AIMS 65 score with Child-Pugh score, MELD score and ALBI score for predicting the outcome in patients with upper GI bleed in chronic liver disease. Material and Methods:Data of patients with chronic Liver disease secondary to ethanol were retrospectively reviewed. Child Pugh score, MELD score, ALBI score and AIMS 65 score were calculated for the patients and results . ROC curves derived from comparison with outcome and were analysed. Results:In our study conducted on 112 patients, the age distribution was between 20-85 years with mean age of patients being 46.47 ± 10.9 years, sex ratio Male: Female: 105:7 with mortality rate of 33.92%. The Area under curves of ROC of AIMS65, Child Pugh score, MELD score, ALBI score was 0.779, 0.864, 0.763 and 0.777 respectively.Conclusion: AIMS 65 is a simple and non-endoscopic score for the prediction of in hospital mortality. No statistical difference was observed between AIMS-65 and other scores such as Child Pugh score, ALBI and MELD score.How to cite this article: Nagaraja BS, Madhumathi R, Chidananda V, Sanjeet SB,Abhiman Shetty, Mahadev H Malge. A comparative study of AIMS 65 score with other scoring systems to predict outcomes in patients with upper GI bleed in chronic liver disease.

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“…This study included 120 cirrhotic patients with acute variceal bleeding, admitted at Department of Tropical Medicine and Gastroenterology in Sohag University Hospital during 2015-2016. The Results of the study states that AIMS65 score which was used for the study is found to bethe best simple and applicable scoring system to independently predict mortality in those patients [1].…”

Section: Editor Notementioning

confidence: 99%

Hepatic Functions and its Disorders

Xuefeng¹,

Park²

2016

J Liver

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Scoring Systems and Risk Stratification in Cirrhotic Patients with Acute Variceal Bleeding "Scoring in Variceal Bleeding"

Cited by 3 publications

References 25 publications

Usefulness of the d-dimer to albumin ratio for risk assessment in patients with acute variceal bleeding at the emergency department: retrospective observational study

Usefulness of the d-dimer to albumin ratio for risk assessment in patients with acute variceal bleeding at the emergency department: retrospective observational study

A Comparative Study of AIMS 65 Score with other Scoring Systems to Predict Outcomes in Patients with Upper GI Bleed in Chronic Liver Disease

Hepatic Functions and its Disorders

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