2023
DOI: 10.1096/fj.202300786r
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CYP eicosanoid pathway mediates colon cancer‐promoting effects of dietary linoleic acid

Abstract: Human and animal studies support that consuming a high level of linoleic acid (LA, 18:2ω‐6), an essential fatty acid and key component of the human diet, increases the risk of colon cancer. However, results from human studies have been inconsistent, making it challenging to establish dietary recommendations for optimal LA intake. Given the importance of LA in the human diet, it is crucial to better understand the molecular mechanisms underlying its potential colon cancer‐promoting effects. Using LC‐MS/MS‐based… Show more

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Cited by 7 publications
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References 57 publications
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