2020
DOI: 10.21203/rs.3.rs-36118/v1
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Screening and identification of key biomarkers in breast cancer with brain metastasis: Evidence from bioinformatic analysis

Abstract: Purpose. Breast cancer (BC) has a poor prognosis when brain metastases (BM) occur, and the treatment effect is limited. In this study, we aim to identify representative candidate biomarkers for clinical prognosis of patients with BM and explore the mechanisms underlying the progression of BC.Methods. Herein, we examined the Microarray datasets (GSE125989) obtained from the Gene Expression Omnibus database to find the target genes in BC patients with BM. We employed the GEO2R tool to filter the differentially e… Show more

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