Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis

Plummer, Faye; Manea, Laura; Trépel, Dominic; McMillan, Dean

doi:10.1016/j.genhosppsych.2015.11.005

Cited by 1,275 publications

(998 citation statements)

References 46 publications

Supporting

Mentioning

872

Contrasting

Unclassified

Order By: Relevance

“…These four items have been shown to have high discriminative power in studies with the extended versions. 29,30 A score from zero to 3 points is attributed to each item, for a maximum score of 12 points, 6 for anxiety and 6 for depression. A score X 3 in the first two questions indicates anxiety and a score X 3 in the other two questions indicates depression.…”

Section: Anxiety and Depressionmentioning

confidence: 99%

Mental health in medical residents: relationship with personal, work-related, and sociodemographic variables

Pereira-Lima

Loureiro

Crippa

2016

Rev. Bras. Psiquiatr.

View full text Add to dashboard Cite

Section: Anxiety and Depressionmentioning

confidence: 99%

Mental health in medical residents: relationship with personal, work-related, and sociodemographic variables

Pereira-Lima

Loureiro

Crippa

2016

Rev. Bras. Psiquiatr.

View full text Add to dashboard Cite

“…Indeed, there continues to be recognition that, as discussed in the background section, clinical characteristics and statistical decisions both influence the selection of most appropriate cut-off [14]. We also acknowledge that there is greater uncertainty associated with the use of the clinical cut-offs for the two instruments as a screen for caseness in comparison with their use for diagnostic purposes [49–51]. It will be interesting in future studies to examine this issue also with respect to the Deaf population and the cut-offs now established for the instruments in BSL.…”

Section: Discussionmentioning

confidence: 99%

The theoretical and practical determination of clinical cut-offs for the British Sign Language versions of PHQ-9 and GAD-7

et al. 2016

View full text Add to dashboard Cite

BackgroundThe PHQ-9 and the GAD-7 assess depression and anxiety respectively. There are standardised, reliability-tested versions in BSL (British Sign Language) that are used with Deaf users of the IAPT service. The aim of this study is to determine their appropriate clinical cut-offs when used with Deaf people who sign and to examine the operating characteristics for PHQ-9 BSL and GAD-7 BSL with a clinical Deaf population.MethodsTwo datasets were compared: (i) dataset (n = 502) from a specialist IAPT service for Deaf people; and (ii) dataset (n = 85) from our existing study of Deaf people who self-reported having no mental health difficulties. Parameter estimates, with the precision of AUC value, sensitivity, specificity, positive predicted value (ppv) and negative predicted value (npv), were carried out to provide the details of the clinical cut-offs. Three statistical choices were included: Maximising (Youden: maximising sensitivity + specificity), Equalising (Sensitivity = Specificity) and Prioritising treatment (False Negative twice as bad as False Positive). Standard measures (as defined by IAPT) were applied to examine caseness, recovery, reliable change and reliable recovery for the first dataset.ResultsThe clinical cut-offs for PHQ-9 BSL and GAD-7 BSL are 8 and 6 respectively. This compares with the original English version cut-offs in the hearing population of 10 and 8 respectively. The three different statistical choices for calculating clinical cut-offs all showed a lower clinical cut-off for the Deaf population with respect to the PHQ-9 BSL and GAD-7 BSL with the exception of the Maximising criteria when used with the PHQ-9 BSL. Applying the new clinical cut-offs, the percentage of Deaf BSL IAPT service users showing reliable recovery is 54.0 % compared to 63.7 % using the cut-off scores used for English speaking hearing people. These compare favourably with national IAPT data for the general population.ConclusionsThe correct clinical cut-offs for the PHQ-9 BSL and GAD-7 BSL enable meaningful measures of clinical effectiveness and facilitate appropriate access to treatment when required.

show abstract

“…The PHQ-9 and the GAD-7 will be used to assess depression [42] and anxiety [43, 44]. All items are scored on a 4-point Likert scale (0 = not at all, 1 = several days; 2 = more than half of the days; 3 = nearly all days).…”

Section: Methodsmentioning

confidence: 99%

Effectiveness of pulmonary rehabilitation for patients with asthma: study protocol of a randomized controlled trial (EPRA)

et al. 2017

View full text Add to dashboard Cite

BackgroundAsthma patients are enrolled in multimodal pulmonary rehabilitation (PR) programs. However, available data for the effectiveness of PR in asthma are sparse. Therefore, the primary aim of this randomized control trial (RCT) is to evaluate short-term (end of rehabilitation) and intermediate-term effectiveness (3 months after rehabilitation) of PR for patients with asthma regarding asthma control (primary outcome) and other outcomes. Secondly, moderator effects of gender, age, baseline asthma control, quality of life, and anxiety will be examined. Thirdly, a longitudinal follow-up study will explore the course of the outcomes over one year and the annual costs.MethodsThe EPRA study is a single-center randomized controlled waiting-list trial in the Bad Reichenhall Clinic. Inclusion criteria include a referral diagnosis for uncontrolled asthma, no cognitive impairment and no very severe co-morbidities that indicate significantly greater illness morbidity than asthma alone. In the intervention group (IG), participants will start PR within 4 weeks after randomization; participants of the control group (CG) will start PR 20 weeks after randomization. Data will be assessed at randomization (T0), after 4 weeks (T1; IG: begin of PR), 7 weeks (T2; IG: end of PR), and 20 weeks (T3, CG: begin of PR). The primary outcome is asthma control at T2/T3. Secondary outcomes are health-related quality of life, functional exercise capacity, dyspnea, anxiety, depression, subjective self-management skills, illness perceptions, sick leave and subjective work ability. Outcomes will be analyzed with analysis of covariance, including baseline values of the respective outcomes as covariates. Healthcare costs will be analyzed with a gamma model with a log-link.A longitudinal follow-up study will generate additional data at 3/6/9/12 months after PR for both IG and CG. Latent change models will be used to analyze the course of the primary and secondary outcomes. Annual cost differences before and after rehabilitation will be compared by paired t-test.DiscussionThis RCT will determine the effectiveness of a complex inpatient PR for asthma patients concerning asthma control. Furthermore, important medical and economic information regarding the effectiveness of PR as part of the long-term management of patients with uncontrolled asthma will be generated.Trial registrationGerman Clinical Trials Register (DRKS00007740, May 15, 2015). Protocol version: 1.0 (December, 23, 2016).

show abstract

Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis

Cited by 1,275 publications

References 46 publications

Mental health in medical residents: relationship with personal, work-related, and sociodemographic variables

Mental health in medical residents: relationship with personal, work-related, and sociodemographic variables

The theoretical and practical determination of clinical cut-offs for the British Sign Language versions of PHQ-9 and GAD-7

Effectiveness of pulmonary rehabilitation for patients with asthma: study protocol of a randomized controlled trial (EPRA)

Contact Info

Product

Resources

About