Screening for Chronic Hepatitis B in Patients Undergoing Chemotherapy for Lymphoma or Colon Cancer

Screening for viral hepatitis B infection in cancer patients before receiving chemotherapy – A systematic review and meta‐analysis

“…35,43 Characteristics of these studies, published between 2010 and 2021, with varied sample sizes from 49 to 227,914 patients, are displayed in Table 1. Among the 29 studies, six conference abstracts 26,[29][30][31]35,43 with sufficient information on HBV screening counts were also included. The studies reported hematologic malignancy (10 studies), [27][28][29][30]34,41,43,45,48,54 solid malignancy (four studies), 31,44,47,50 or a combination of both (15 studies).…”

“…The studies reported hematologic malignancy (10 studies), [27][28][29][30]34,41,43,45,48,54 solid malignancy (four studies), 31,44,47,50 or a combination of both (15 studies). 26,32,33,[35][36][37][38][39][40]42,46,49,[51][52][53] The studies also included rituximab-containing (seven studies), 27,28,30,34,41,43,54 non-rituximab (four studies), 31,42,44,46 or both regimens (seven studies), 32,33,36,38,40,48,49 and the remaining 11 studies did not specify chemotherapy types. 26,29,34,…”

“…26,32,33,[35][36][37][38][39][40]42,46,49,[51][52][53] The studies also included rituximab-containing (seven studies), 27,28,30,34,41,43,54 non-rituximab (four studies), 31,42,44,46 or both regimens (seven studies), 32,33,36,38,40,48,49 and the remaining 11 studies did not specify chemotherapy types. 26,29,34,37,38,45,47,[50][51][52][53] Nineteen studies 27,28,[32][33][34][35][36]…”

“…The remaining 10 studies only utilized HBsAg testing for HBV screening. 26,[29][30][31]37,41,45,47,51,53 Most studies (n = 17) originated from Asia (n = 4 from Australia and Taiwan, n = 3 from Japan, n = 2 from Turkey and China, and n = 1 from Thailand and Singapore), while the other 11 studies were conducted in the United States and only one in Spain (Figure 2). HBV endemicity was classified as low endemic in 19 studies, [32][33][34][35]38,39,[40][41][42][43]45,46,48,49,51 lower intermediate endemic in four studies, 31,47,50,54 higher intermediate endemic in four studies, 36,44,52,53 and high endemic in two studies.…”

“…HBV endemicity was classified as low endemic in 19 studies, [32][33][34][35]38,39,[40][41][42][43]45,46,48,49,51 lower intermediate endemic in four studies, 31,47,50,54 higher intermediate endemic in four studies, 36,44,52,53 and high endemic in two studies. 37,39 To analyze the trend in screening rates over time, the studies were categorized into three 5-year periods: 13 studies from 2006 to 2010, [26][27][28][31][32][33][34]36,[40][41][42]50,54 19 studies from 2011 to 2015, 29,30,33,35,[37][38][39][40]42,43,[45]…”