Screening for depression in cancer patients using the PHQ-9: The accuracy of somatic compared to non-somatic items

Grapp, Miriam; Terhoeven, Valentin; Nikendei, Christoph; Friederich, Hans‐Christoph; Maatouk, Imad

doi:10.1016/j.jad.2019.05.026

Cited by 21 publications

(31 citation statements)

References 43 publications

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“…As such, our findings are in line with recent findings concluding that somatic symptoms should be included in the assessment of depressive symptoms among chronic ill patients . Our findings also support previous research showing the unidimensionality of the PHQ‐9 and therefore warrant using a total score.…”

Section: Discussionsupporting

confidence: 92%

“…Our findings also support previous research showing the unidimensionality of the PHQ‐9 and therefore warrant using a total score. Previous studies investigating distinct depressive symptoms have mostly dichotomized depression, and so our study adds to previous research by showing that somatic symptoms sleep problems and fatigue mainly discriminate for mild depression, whereas somatic symptoms appetite changes and concentration difficulty discriminate evenly across depression severity.…”

Section: Discussionsupporting

confidence: 53%

“…The PHQ‐9 is a valid self‐report instrument based on the DSM‐IV diagnosis of a depressive disorder, consisting of nine items that can be scored from 0 to 3, resulting in a total score between 0 and 27. Depression severity categories are no (0‐4), mild, moderate (10‐14), moderately‐severe (15–19), and severe depression (20–27) . Reliability was good (α = 0.87 and ω = 0.89) in our study.…”

Section: Methodssupporting

confidence: 48%

“…It is well known that somatic symptoms of depression may overlap with symptoms of the illness and its treatment, hereby increasing the risk of false‐positive diagnoses . Whether or not to include somatic symptoms in the assessment of depressive symptoms in cancer patients has therefore been an on‐going debate over the past decades, with recent studies suggesting to include somatic symptoms also in persons with a somatic condition …”

Section: Introductionmentioning

confidence: 99%

“…By doing so, they overlooked the role of distinct depression symptoms as was recommended more recently, given the heterogeneity with in the somatic or cognitive/affective domain . Another limitation is the focus on “depressed” versus “not depressed”, with a call for more research addressing the continuum of depression severity …”

Section: Introductionmentioning

confidence: 99%

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The value of distinct depressive symptoms (PHQ‐9) to differentiate depression severity in cancer survivors: An item response approach

et al. 2019

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 53%

Section: Methodssupporting

confidence: 48%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The value of distinct depressive symptoms (PHQ‐9) to differentiate depression severity in cancer survivors: An item response approach

et al. 2019

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Suicidal ideation in advanced cancer patients without major depressive disorder

Tang

Pang

et al. 2022

Psycho-Oncology

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Introduction Major depressive disorder (MDD) is associated with an increased risk of suicide and suicide attempt among cancer patients. However, we do not know how many cancer patients without MDD have suicidal ideation (SI). Objectives This study aimed to investigate the prevalence, characteristics and correlated factors of SI among advanced cancer patients without MDD. Methods This is a multi‐center, cross‐sectional study based on an electronic patient‐reported outcome systems in patients who were diagnosed with advanced lung, liver, gastric, esophageal, colorectal or breast cancer, the top six prevalent cancers in China. A total of 2930 advanced cancer patients were recruited from 10 regional representative cancer centers across China from August 2019 to December 2020. Patients completed the Patient Health Questionnaire‐9 regarding if they had thoughts of being better off dead or of hurting themselves in some way in the previous 2 weeks. Patients also completed the symptom inventory and quality of life assessment. Generalized estimating equation model was performed to explore the correlated factors associated with SI among the patients without MDD. Results The overall prevalence of SI among advanced cancer patients without MDD was 13.1%. The prevalence was higher in older patients. After adjusted for existing conditions, patients with vomiting symptom (p < 0.001), poorer life quality (p < 0.001), and middle education level (p = 0.031) were correlated factors of SI. Conclusions The suicidal ideation is common in advanced cancer patients without MDD. Patients with vomiting, poor quality of life, and middle education level should be screened and monitored for suicidal ideation even without MDD. Clinical Trial Information ChiCTR1900024957.

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Depression profile in malignancy patients attending otorhinolaryngology clinic

Khadilkar

Pai

Rai

et al. 2020

Eur Arch Otorhinolaryngol

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Purpose Patients with malignancy quite often suffer from physical as well as psychological symptoms due to the shattering diagnosis, and prolonged, incapacitating management. The frequency of the depressive disorder in malignancy is around 8-40%. The present study aims at analysing the socio-demographic profile and magnitude of depressive disorders in patients with malignancy. Methods A cross-sectional study was conducted in malignancy patients attending an Ear Nose Throat department using the PHQ-9 questionnaire. Results Total PHQ-9 score ranged from 0 to 19; the mean score was 8.46. Major depressive disorder was seen in 4 (8%) cases, while other depressive disorder occurred in 22 (44%) cases. Mild severity of symptoms was noted in 15 (30%) of the patients. High statistical significance was noted between PHQ-9 score for MDD and other depressive disorder (p value < 0.001). Conclusion The profile of depressive disorders in malignancy varies; PHQ-9 can be used as a good tool for early detection.

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Screening for depression in cancer patients using the PHQ-9: The accuracy of somatic compared to non-somatic items

Cited by 21 publications

References 43 publications

The value of distinct depressive symptoms (PHQ‐9) to differentiate depression severity in cancer survivors: An item response approach

The value of distinct depressive symptoms (PHQ‐9) to differentiate depression severity in cancer survivors: An item response approach

Suicidal ideation in advanced cancer patients without major depressive disorder

Depression profile in malignancy patients attending otorhinolaryngology clinic

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