Screening, isolation and optimization of anti–white spot syndrome virus drug derived from terrestrial plants

Abstract

The drug TP22C derived from Momordica charantia is a potent anti-white spot syndrome virus drug.

Azospirillum brasilense increased salt tolerance of jojoba during in vitro rooting

“…IC 50 is calculated by regression and represents the concentration of a substance needed to inhibit a given biological process (or component of a process) by 50%. It is commonly used as a measure of antagonist drug potency in pharmacological research (Ghosh and Chakraborty, 2013). To our …”

Molecular Mechanisms of White Spot Syndrome Virus Infection and Perspectives on Treatments

“…Examples include extracts of Cynodon dactylon and Ceriops tagal [ 216 , 217 ] that have shown protective effects against WSSV in P. monodon . Extracts from the seaweed Sagrassum weighti have been shown to have a significant effect in reducing WSSV infection in both the Indian prawn ( P. indicus ) and freshwater crab ( Paratelphusa hydrodomous ) [ 218 , 219 ]. Oral administration of a plant extract from Momordica charantia has been shown to result in an 86% survivorship in L. vannamei infected with WSSV [ 219 ].…”

“…Extracts from the seaweed Sagrassum weighti have been shown to have a significant effect in reducing WSSV infection in both the Indian prawn ( P. indicus ) and freshwater crab ( Paratelphusa hydrodomous ) [ 218 , 219 ]. Oral administration of a plant extract from Momordica charantia has been shown to result in an 86% survivorship in L. vannamei infected with WSSV [ 219 ]. Furthermore, several diets based on extracts from Agathi grandiflora have also been shown to decrease mortality rates substantially in WSSV-infected Fenneropenaeus indicus [ 220 ].…”

Melia azedarach L. Fruit Extract as a potencial candidate in controlling the Neuraeschna Hagen, 1867 (Odonata: Aeshnidae), predominant predators for fish fingerlings

“…These products are rich in a variety of nutrients and serve as a repository of new additives for food for aquatic animals. Research has show the use of natural products to increase the digestibility of nutrients, improve food conversion, increase weight gain, control parasites, as immunostimulants, antiviral and antibacterial activity (Ghosh et al, 2014;Chakraborty and Ghosh, 2014;Xiang & Zhou, 2000;Ardó et al, 2008;Abutbul et al, 2005). Other studies have shown the use of natural products with the use of Aloe vera L. in water transport to control the stress in Matrinchã, Brycon amazonicus (Zanuzzo, 2010), in the control of monogenetics in Astronotus ocellatus, among young tambaqui Colossoma macropomum (Claudiano et al, 2009), and in the control of white spot virus in Penaeus monodon (Balasubramanian et al, 2007;Balasubramanian et al, 2008).…”