Searching for a physiologically meaningful parameter for aortic biomechanics—is energy loss the way?

Reply from authors: Toward physiologically meaningful biomechanical parameters from ex vivo biaxial testing

“…Stemming from the Commentary by Tang and colleagues 1 on our article, 2 we were excited to be invited to elaborate more on the biaxial ex vivo biomechanical parameters for assessing ascending aortic aneurysms. Particularly, Tang and colleagues 2 raise an excellent point regarding the limitations of ex vivo testing.…”

“…Our research group is cautiously optimistic about energy loss as presented by Chung and colleagues. 3 We are very excited to see the rigorous analysis conducted by Tang and colleagues 1 , 4 on sensitivity of energy loss as well as the meaningful discussion on the physics behind this parameter. Studies like the one by Tang and colleagues 4 raise our confidence in using this parameter in the future.…”