2024
DOI: 10.1021/acs.jmedchem.3c01750
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Searching for Conjugates as New Structures for Antifungal Therapies

Izabela Muszalska-Kolos,
Piotr Mariusz Dwiecki

Abstract: The progressive increase in fungal infections and the decrease in the effectiveness of current therapy explain research on new drugs. The synthesis of compounds with proven antifungal activity, favorable physicochemical and pharmacokinetic properties affecting their pharmaceutical availability and bioavailability, and limiting or eliminating side effects has become the goal of many studies. The publication describes the directions of searching for new compounds with antifungal activity, focusing on conjugates.… Show more

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