Seasonal Changes in the Structure and Function of Gut Microbiota in the Muskrat (Ondatra zibethicus)

Song, Fengcheng; Xu, Yuanming; Peng, Peng; Hongxu, LI; Zheng, Ranxi; Zhang, Haolin; Han, Yingying; Wang, Qiang; Yuan, Zhengrong

doi:10.3390/metabo13020248

Cited by 4 publications

(3 citation statements)

References 68 publications

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“…The co‐varied gut bacterial community with seasons might be one of the strategies for semi‐captive Przewalski's gazelles to get through the harsh winter in the high plateau. The results of our study were in line with previous studies and suggested that the seasonal shift of the gut bacterial community is significant for the improvement of animal fitness (Guo et al 2021, Jiang et al 2021, Huang et al 2022, Song et al 2023).…”

Section: Discussionsupporting

confidence: 92%

Semi‐captive Przewalski's gazelles cope with winter adversity by adjusting their gut bacterial communities

Zhang,

Xiang,

Liu

et al. 2024

J Wildl Manag

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The intestinal microbiota plays an important role in the digestion and absorption of nutrients in animals. To address the challenge of conservation, many endangered wildlife are kept in captive or semi‐captive conditions. Numerous studies have been conducted on the intestinal microbiota of captive animals, but little information is available on the intestinal microbiota of semi‐captive animals, such as Przewalski's gazelle (Procapra przewalskii), which is an endangered ungulate species only distributed around Qinghai Lake in China. In this study, we used high‐throughput sequencing methods to analyze the gut bacterial community of semi‐captive Przewalski's gazelles during summer and winter. There were differences in the gut bacterial community composition between the 2 seasons, with higher bacterial diversity in winter. Deterministic processes dominated the bacterial community assembly in both seasons. There was a greater influence of heterogeneous selection in winter compared to summer, suggesting that there was more intestinal environmental filtering and selection on shaping the gut bacterial community during winter. There were more potential probiotic bacteria and fewer potential pathogens in winter compared to summer. Overall, stronger heterogeneous selection in winter might enhance gut selection for potential probiotic bacteria and filter out potential pathogens in Przewalski's gazelles, allowing them to adapt to the harsh living conditions in winter. Our study clarified that seasonal fluctuations trigger shifts in bacterial communities, which have potential benefits for Przewalski's gazelles. These results could provide valuable information for managing semi‐captive populations and for future wild releases of Przewalski's gazelles.

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Section: Discussionsupporting

confidence: 92%

Semi‐captive Przewalski's gazelles cope with winter adversity by adjusting their gut bacterial communities

Zhang,

Xiang,

Liu

et al. 2024

J Wildl Manag

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“…Before this study, we also performed a metagenomic analysis of the gut microbiota of another seasonal breeding animal, the muskrat ( Ondatra zibethicus ) [ 85 ]. Comparing these two results, we found that their gut microbiota had the opposite ratios of Firmicutes to Bacteroidetes concerning the season.…”

Section: Discussionmentioning

confidence: 99%

Seasonal Variation in Gut Microbiota of the Wild Daurian Ground Squirrel (Spermophilus dauricus): Metagenomic Insights into Seasonal Breeding

Song

Zhang

et al. 2023

Animals

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The Spermophilus dauricus, the wild Daurian ground squirrel, is known to exhibit seasonal breeding behavior. Although the importance of gut microbiota in animal digestion, metabolism, and immunity is well-established, the correlation between gut microbiota and seasonal breeding in this species remains inadequately explored. In the present study, using metagenomic sequencing technology, the compositions and functions of the gut microbiota of wild Daurian ground squirrels in different breeding seasons were explored. The dominant gut microbial phyla were Firmicutes and Bacteroidetes. The Firmicutes were predominant in the breeding season, whereas Bacteroidetes were predominant in the non-breeding season. At the genus level, Lactobacillus accumulated during the breeding season, whereas Odoribacter and Alistipes increased during the non-breeding season. GO (Gene Ontology) and KEGG (Kyoto Encyclopedia of Genes and Genome) annotations indicated that genes in gut samples were highly associated with metabolic functions. The differential expression gene analysis showed that genes related to the phosphotransferase system, cysteine, and methionine metabolism were highly expressed during the breeding season, whereas the non-breeding season upregulated genes were enriched in starch and sucrose metabolism and bacterial chemotaxis pathways. In conclusion, this study could provide a reference for investigating gut microbiota in seasonal breeding animals and offer new insight into gut microbial function.

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“…сказываться на здоровье макроорганизма и препятствовать канцерогенезу, развитию воспаления и метаболических расстройств [34]. Кроме того, ряд исследований продемонстрировали возможность сезонных изменений кишечной микробиоты как у животных, так и у людей, что может быть обусловлено изменением не только характера питания, но и длины светового дня [35][36][37][38][39].…”

Section: прикладные аспекты эндокринологии и кардиологииunclassified

Association between gut microbiota and thyroid dysfunction

Tulsky,

Myrinova,

Shchetinina

et al. 2024

Medicinskij sovet

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The article is devoted to modern researches about the potential role of gut microbiota in the development of thyroid pathology. Gut microbiota plays a major role both in the formation and maintenance of human health and in the pathogenesis of a wide range of diseases. There is evidence of the relationship between the gut microbiota and the immune system, the risk of developing several malignant and autoimmune diseases. The article discusses the functions of the gut microbiota and the factors that determine its composition. Studies have shown a connection between the gut microbiota and the thyroid gland, which formed the basis for the formation of the theory of the gut-thyroid axis. It has been shown that the gut microbiota takes part in the metabolism of thyroid hormones and ensures their enterohepatic circulation. It is assumed that one of the links between the thyroid gland and gastrointestinal microorganisms is the immune system. The results of studies examining the taxonomic composition of the gut microbiota in patients with autoimmune thyroiditis and Graves’ disease are presented. It is hypothesized that the composition of the gut microbiota may influence the requirement for levothyroxine, especially in patients with subclinical hypothyroidism. On the other hand, levothyroxine, to a lesser extent, directly hypothyroidism as a result of autoimmune thyroiditis are associated with bacterial overgrowth syndrome despite the achievement of euthyroidism, and may affect the composition of the microbiota. Even though autoimmune thyroid diseases are quite common in the general population, little work has been done on this issue. More reliable basic and clinical researches are needed to identify specific relationships and mechanisms of development of thyroid pathology depending on changes in the composition of the gut microbiota, as well as to assess the potential for therapeutic use.

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Seasonal Changes in the Structure and Function of Gut Microbiota in the Muskrat (Ondatra zibethicus)

Cited by 4 publications

References 68 publications

Semi‐captive Przewalski's gazelles cope with winter adversity by adjusting their gut bacterial communities

Semi‐captive Przewalski's gazelles cope with winter adversity by adjusting their gut bacterial communities

Seasonal Variation in Gut Microbiota of the Wild Daurian Ground Squirrel (Spermophilus dauricus): Metagenomic Insights into Seasonal Breeding

Association between gut microbiota and thyroid dysfunction

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