Seasonal variation in carbohydrate and lipid metabolism of yellow perch (Perca flavescens) chronically exposed to metals in the field

Levesque, Haude; Moon, Thomas W.; Campbell, Peter G. C.; Hontela, Alice

doi:10.1016/s0166-445x(02)00012-7

Cited by 200 publications

(133 citation statements)

References 27 publications

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“…Scott et al (2003) reported that plasma cortisol levels in rainbow trout increased when fish were exposed to an alarm substance, a chemical released from skin epithelium, and this increase was inhibited by Cd. Other studies provided evidence that the capacity to raise plasma cortisol is impaired in fish exposed to organic pollutants (Aluru et al, 2004) and metals (Brodeur et al, 1997;Norris, 2000;Lévesque et al, 2002). Our data indicate that exposure to Cu alone disrupts the HPI axis since fish exposed to Cu exhibited an impaired cortisol stress response.…”

Section: Discussionmentioning

confidence: 48%

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Effects of Cu on plasma cortisol and cortisol secretion by adrenocortical cells of rainbow trout (Oncorhynchus mykiss)

2006

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Fish are exposed to multiple stressors, often acting concurrently, in their environment. To evaluate the potential of Cu to act as a chemical stressor, rainbow trout (Oncorhynchus mykiss) were exposed to Cu (30 or 80 g/l) for 30 days in the laboratory and they were subjected to a physical stressor (1 min air exposure) before sampling. Physiological stress indicators in the whole fish as well as cortisol secretion by adrenocortical cells in vitro were measured. Fish exposed to Cu had a lower condition factor, hepatosomatic index, plasma glucose, hepatic glycogen and gill Na + /K + -ATPase activity compared to controls. Exposure to Cu did not have an effect on basal plasma cortisol (fish sampled without air exposure stress) however, the air exposure-induced increase in plasma cortisol was lower in fish exposed to Cu. Cortisol secretion stimulated by ACTH in vitro was greater in adrenocortical cells isolated from fish exposed to Cu in vivo but in vitro exposure to Cu consistently impaired cortisol secretion. Our results indicate that Cu at high concentrations disrupts cortisol secretion through a direct toxic effect on adrenocortical cells while low concentrations resulting from a 30-day exposure to environmentally relevant Cu concentrations enhances cortisol secretion in response to ACTH in vitro.

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Section: Discussionmentioning

confidence: 48%

“…Liver glycogen was assayed with a method described in Lévesque et al (2002). Frozen liver (≈0.1 g) was digested in 10% KOH and hydrolysed with amyloglucosidase (Sigma).…”

Section: Glucose and Glycogenmentioning

confidence: 99%

Effects of Cu on plasma cortisol and cortisol secretion by adrenocortical cells of rainbow trout (Oncorhynchus mykiss)

2006

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“…It has been suggested that reallocation of energy toward detoxification, restoring homeostasis and tissue repair following contaminant exposure has an impact on growth (Wendelaar Bonga, 1997;Levesque et al, 2002). Fish exposed to 100 g l −1 ATZ had reduced food intake during the exposure period, and thus may have had to replenish energy stores during the first month in SW at the expense of growth rate.…”

Section: Treatmentsmentioning

confidence: 99%

“…The smolts in the present study were not reproductively mature, so the significance of this observation is not clear. Decreases in GSI are known to occur in reproductive female and male fish exposed to contaminants such as mercury, cadmium, copper and pesticides (Gimeno et al, 1998;Levesque et al, 2002;Cardinali et al, 2004). Exposure of goldfish to 1000 g l −1 ATZ decreased plasma testosterone (Spano et al, 2004).…”

Section: Treatmentsmentioning

confidence: 99%

Effects of hexazinone and atrazine on the physiology and endocrinology of smolt development in Atlantic salmon

2007

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Exposure to hexazinone (HEX) and atrazine (ATZ), highly mobile and widely used herbicides along rivers in the United States, is potentially harmful to Atlantic salmon, which have been listed as an endangered species. To determine the effects of these contaminants on smolt development, juvenile Atlantic salmon were exposed under flow-through conditions to 100 g l −1 HEX, 10 and 100 g l −1 ATZ in fresh water (FW) for 21 days at 10 • C beginning in mid-April. Twelve fish per treatment were sampled in FW, following a 24 h seawater (SW) challenge and after growth for 3 months in SW. Exposure to 100 g l −1 HEX or 10 g l −1 ATZ caused no mortalities of smolts in FW or after SW challenge, while 9% of the fish exposed to 100 g l −1 ATZ died during exposure. Fish exposed to 100 g l −1 ATZ reduced feeding after 10 days of exposure and had an impaired growth rate in FW and during the first month in SW; compensatory growth occurred in the second and third month in SW. HEX and ATZ at 10 g l −1 exposure had no effect on plasma levels of cortisol, growth hormone (GH), insulin growth factor I (IGF-I), thyroxine (T 4 ) and plasma 3,5,3 -triiodo-l-thyronine (T 3 ), Cl − , Mg 2+ , Na + , Ca 2+ in FW or after SW challenge. FW smolts exposed to 100 g l −1 ATZ had decreased plasma Cl − , Mg 2+ , Na + and Ca 2+ ions and increased cortisol. No effect on plasma levels of GH, IGF-I, T 4 or T 3 was found in FW smolts exposed to 100 g l −1 ATZ. Following SW challenge, fish previously exposed to 100 g l −1 ATZ had significant increases in hematocrit, plasma cortisol, Cl − , Mg 2+ , Na + , Ca 2+ and a decrease in T 4 and T 3 . It is concluded that under the conditions imposed in this study, HEX does not affect salinity tolerance of Atlantic salmon smolts, while ATZ causes ionoregulatory, growth and endocrine disturbance.

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“…An increase in plasma GPT and GOT activities due to metals (Zn, Cu and Cd) was also found in experimental conditions (Zikic et al, 2001) as well as in fish chronically exposed to metals (Levesque et al, 2002). Tietz (1987) and Campel (1984) reported that, these enzymes liberate to the blood stream when the hepatic parenchymal cells are damaged.…”

Section: Discussionmentioning

confidence: 75%

Pathological changes in liver structure and function of Oreochromis niloticus experimentally exposed to Escherichia coli

Yacoub¹,

Sabra²,

Al-Kourashi³

2017

IJBB

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Seasonal variation in carbohydrate and lipid metabolism of yellow perch (Perca flavescens) chronically exposed to metals in the field

Cited by 200 publications

References 27 publications

Effects of Cu on plasma cortisol and cortisol secretion by adrenocortical cells of rainbow trout (Oncorhynchus mykiss)

Effects of Cu on plasma cortisol and cortisol secretion by adrenocortical cells of rainbow trout (Oncorhynchus mykiss)

Effects of hexazinone and atrazine on the physiology and endocrinology of smolt development in Atlantic salmon

Pathological changes in liver structure and function of Oreochromis niloticus experimentally exposed to Escherichia coli

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