Sebaceous Hyperplasia Treated With a 1450-nm Diode Laser

No, David; McClaren, Marla L.; Chotzen, Vera A.; Kilmer, Suzanne L.

doi:10.1111/j.1524-4725.2004.30105.x

Cited by 22 publications

(15 citation statements)

References 8 publications

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“…Other procedures that have also been used include excision, electrocauterization, cryotherapy, shaving, curettage and cauterization with chemical agents used topically, although there is a risk of depigmentation or scarring with these latter options. [16][17][18][19][20][21][22][23][24][25] Many laboratory studies have shown the effect of androgens on the sebaceous glands. A review of the literature on several research models confirmed the effect of androgens in triggering the activity of the sebaceous glands and indicated which of these hormones may be implicated in triggering these glands.…”

Section: Introductionmentioning

confidence: 99%

Hiperplasia sebácea cutânea: estudo piloto para a correlação da doença com hormônios androgênios

Tagliolatto¹,

Alchorne

Enokihara

2011

An. Bras. Dermatol.

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FUNDAMENTOS: As glândulas sebáceas são suscetíveis à ação dos hormônios androgênios e apresentam proliferação benigna com a idade, ou seja, hiperplasia. OBJETIVOS: Estudo piloto para verificar se há correlação entre a taxa de hormônios masculinos circulantes e o aumento da incidência da hiperplasia das glândulas sebáceas. MÉTODOS: 16 pacientes do sexo feminino, com diagnóstico de hiperplasia sebácea cutânea, foram comparados a um grupo-controle de mesmo gênero e idades semelhantes, sem a doença. Ambos os grupos foram submetidos a testes de dosagem sanguínea para avaliação das taxas de hormônios androgênios circulantes (testosterona livre e total, androstenediona). Os resultados foram tabulados e analisados estatisticamente. RESULTADOS: Os dados demonstraram não haver mudanças nos níveis de hormônios masculinos circulantes dos pacientes com hiperplasia sebácea cutânea, quando comparados ao grupo-controle. CONCLUSÃO: Os dados sugerem que não há alterações estatisticamente significantes nas taxas dos hormônios circulantes (testosterona livre e total, androstenediona, deidroepiandrosterona, sulfato de deidroepiandrosterona) dos pacientes com hiperplasia sebácea cutânea.

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Section: Introductionmentioning

confidence: 99%

Hiperplasia sebácea cutânea: estudo piloto para a correlação da doença com hormônios androgênios

Tagliolatto¹,

Alchorne

Enokihara

2011

An. Bras. Dermatol.

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“…27 The laser focuses on the water in the skin, which is likely why the upper dermis is heated and therapeutically damaged. 28 Interestingly, the 1450-nm laser appears to induce a systemic effect on the skin, as treatment on only one side of the face in one 2011 study resolved acne lesions on both sides of the face. 29 Unfortunately, in our experience, subsurfacing laser technology has had limited improvement of facial wrinkling.…”

Section: -Nm Diode Laser (Candela Smoothbeam)mentioning

confidence: 99%

Current Laser Resurfacing Technologies: A Review that Delves Beneath the Surface

Preissig

Hamilton

Markus

2012

Seminars in Plastic Surgery

137

134

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).Laser resurfacing technologies represent an exciting development in the cosmetic surgeon's repertoire to improve the tone, texture, and pigmentation of the skin. Although laser resurfacing is not a substitute for a facelift or blepharoplasty, the appropriate laser not only tightens the skin somewhat but also improves the appearance of lentigines, rhytides, skin texture, and a wide variety of scars.There are ablative and nonablative lasers as well as fractionated and nonfractionated lasers. Nonfractionated lasers act on the entire projected surface area of the treated skin, whereas fractionated lasers target an equally distributed portion of the projected area. An easy way to understand the difference is in looking at the pixels that compose a TV image. Nonfractionated devices treat every single pixel whereas fractionated devices treat only a percentage of the pixels in the treatment area.Ablative lasers vaporize tissue and therefore are more aggressive compared with the gentler nonablative lasers that leave the skin intact. Although ablative lasers result in far more down time and a more difficult recovery process, they remain the lasers that produce the most dramatic outcomes. For more severe facial wrinkles, dyspigmentation, and textural skin challenges, the ablative laser is often the treatment of choice.For patients seeking more moderate improvement-without the possible side effects of ablative lasers-nonablative lasers are often ideal. These lasers leave the epidermis intact while producing rejuvenating skin effects. Depending on the technology, nonablative laser treatments may minimize the appearances of finer wrinkles, ameliorate the texture and tone of the skin, and treat dyspigmentation. By comparison, the treatments are gentler and require little to no downtime, but produce a more moderate response.Ultimately, a patient's needs dictate the selection of the ideal laser. In this review, we seek to demystify the differences between the many available lasers and thereby facilitate the identification of the most appropriate laser for the patient. Ablative Nonfractionated LasersAblative skin resurfacing removes the epidermal layer, producing the most dramatic laser-treated results for skin resurfacing. The lasers quickly superheat water molecules in the skin tissue. When the water turns into gas, the skin cells are vaporized in a precise skin-peeling effect. This effect promotes collagen formation and retraction of the dermis and AbstractNumerous laser platforms exist that rejuvenate the skin by resurfacing its upper layers. In varying degrees, these lasers improve the appearance of lentigines and rhytides, eliminate photoaging, soften scarring due to acne and other causes, and treat dyspigmentation. Five major classes of dermatologic lasers are currently in common use: ablative and nonablative lasers in both fractionated and unfractionated forms as well as radiofrequency technologies. The gentler nonablative lasers allow for quicker healing, whereas harsher ablative lasers tend to be more effective. Fract...

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“…The laser spot diameter was 6 mm. Three clinically relevant MCS-LPS patterns [5][6][7][19][20][21][22] were applied on the skin specimens. As illustrated in Figure 2, MCS-LPS-1 involved the longest total cryogen spray time (t CSC 1 ¼ 38 milliseconds).…”

Section: Laser Devicementioning

confidence: 99%

“…A diode laser with a wavelength of 1,450 nm in combination with CSC is clinically used for treatment of acne, acne scarring, and non-ablative photorejuvenation [5][6][7]. The laser light is used to target the dermal sebaceous glands and associated structures, while CSC protects the epidermis.…”

Section: Introductionmentioning

confidence: 99%

Thermal responses of ex vivo human skin during multiple cryogen spurts and 1,450 nm laser pulses

et al. 2006

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Background and Objective: Although cryogen spray cooling (CSC) is used to minimize the risk of epidermal damage during laser dermatologic surgery, concern has been expressed that CSC may induce cryo-injury. The objective of this study is to measure temperature variations at the epidermal-dermal junction in ex vivo human skin during three clinically relevant multiple cryogen spurt-laser pulse sequences (MCS-LPS). Study Design/Materials and Methods: The epidermis of ex vivo human skin was separated from the dermis and a thin-foil thermocouple (13 mm thickness) was inserted between the two layers. Thermocouple depth and epidermal thickness were measured using optical coherence tomography (OCT). Skin specimens were preheated to 308C before the MCS-LPS were initiated. Three MCS-LPS patterns, with total cryogen spray times of 38, 30, and 25 milliseconds respectively, were applied to the specimens in combination with laser fluences of 10 and 14 J/cm 2 , while the thermocouple recorded the temperature changes at the epidermal-dermal junction. Results: The thermocouple effectively recorded fast temperature changes during three MCS-LPS patterns. The lowest temperatures measured corresponded to the sequences with longer pre-cooling cryogen spurts. No subzero temperatures were measured for any of the MCS-LPS patterns under study. Conclusions: The three clinically relevant MCS-LPS patterns evaluated in this study do not cause sub-zero temperatures in ex vivo human skin at the epidermal-dermal junction and, therefore, are unlikely to cause significant cryogen induced epidermal injury.

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Sebaceous Hyperplasia Treated With a 1450-nm Diode Laser

Abstract: The 1450-nm diode laser is effective and safe for the treatment of sebaceous hyperplasia.

Cited by 22 publications

References 8 publications

Hiperplasia sebácea cutânea: estudo piloto para a correlação da doença com hormônios androgênios

Hiperplasia sebácea cutânea: estudo piloto para a correlação da doença com hormônios androgênios

Current Laser Resurfacing Technologies: A Review that Delves Beneath the Surface

Thermal responses of ex vivo human skin during multiple cryogen spurts and 1,450 nm laser pulses

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