Abstract:Cryo-electron tomography (cryo-ET) is a key tool for imaging macromolecules in cellular environments. Together with subtomogram averaging (STA), cryo-ET can be used for structure determination. Weak visibility of many structures in cryo-ET as well as the volume of data required for STA, however, motivate the exploration of advanced image processing for cryo-ET. Compressed sensing is a mathematically rigorous signal processing approach to sampling with far fewer measurements than traditionally required, with si… Show more
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