2009
DOI: 10.1038/nnano.2009.326
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Second window for in vivo imaging

Abstract: Enhanced fluorescence from carbon nanotubes and advances in near-infrared cameras have opened up a new wavelength window for small animal imaging.Near-infrared light (700-2,500 nm) can penetrate biological tissues such as skin and blood more efficiently than visible light because these tissues scatter and absorb less light at longer wavelengths. Simply hold your hand in sunlight and your fingers will glow red owing to the preferential transmission of red and near-infrared light. At wavelengths longer than 950 … Show more

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Cited by 2,466 publications
(1,930 citation statements)
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“…(A) A scheme of nGO-PEG conjugated with anti-CD105 antibody (TRC105) and 1,4,7-triazacyclononane-1,4,7-triacetic acid (NOTA). The latter was used for 64 Cu labeling. (B) Time-dependent in vivo PET imaging of mice bearing 4T1 tumors i.v.…”
Section: Resultsmentioning
confidence: 99%
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“…(A) A scheme of nGO-PEG conjugated with anti-CD105 antibody (TRC105) and 1,4,7-triazacyclononane-1,4,7-triacetic acid (NOTA). The latter was used for 64 Cu labeling. (B) Time-dependent in vivo PET imaging of mice bearing 4T1 tumors i.v.…”
Section: Resultsmentioning
confidence: 99%
“…Based on this method, a number of studies have been explored. Cai and co-workers demonstrated in vivo active tumor targeting using 64 Cu labeled nGO-PEG (54). The in vivo PET imaging results evidenced the active tumor targeting by conjugating nGO-PEG with an antibody, TRC105, to target vasculatures in 4T1 murine breast tumors.…”
Section: Radionuclide-based Imagingmentioning
confidence: 94%
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