Secondary pulmonary syphilis: Case report and review of literature

Youssef, H. Kassem; Blind, A.; Ngaha, F. Chouta; Drénou, Bernard; Nojavan, H.; Michel, Catherine

doi:10.1016/j.annder.2017.11.015

Cited by 12 publications

(4 citation statements)

References 23 publications

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“…On chest imaging, pulmonary syphilis can present as bilateral infiltrates, single or multiple nodules, or, in rare cases, pleural effusion as seen in our case [ 5 ]. A review by Youssef et al reported co-infection with HIV is seen in about 18% of the patients [ 6 ]. These findings coincide with different disease processes often delaying the diagnosis.…”

Section: Discussionmentioning

confidence: 99%

“…The discrepancy between the nontreponemal and treponemal test may also be observed in patients previously treated for syphilis, in very early or late stages of the disease when the non-treponemal test is essentially non-reactive or in individuals with immunocompromised states who cannot mount an appropriate B-cell response [ 11 - 13 ]. Polymerase chain reaction (PCR) on bronchoalveolar lavage (BAL), pleural fluid, lung biopsy, and immunohistochemistry may also be of benefit to identify the indicated spirochete [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

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An Unusual Case of Syphilis With Pulmonary Involvement

Arzoun,

Mohammed,

Saeed

et al. 2024

Cureus

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Syphilis can affect multiple organs in the secondary or tertiary stages of the disease. Recent reports have suggested an increase in the incidence of the disease. Involvement of the lung has been rarely described in syphilis. In this report, we discuss the case of a 26-year-old female with past medical history significant for HIV who presented to the hospital with complaints of shortness of breath and underwent thoracentesis; she was found to have syphilis with pulmonary involvement.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

An Unusual Case of Syphilis With Pulmonary Involvement

Arzoun,

Mohammed,

Saeed

et al. 2024

Cureus

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“…Florencio et al [ 9 ] reported syphilitic pulmonary involvement mimicking lymphoma with polyadenopathy and pulmonary nodules. Kassem Youssef et al [ 10 ] reported a case of syphilitic pulmonary involvement revealed by dyspnea, with thoracic imaging showing interstitial lung pattern, moderate pleural effusion, and hilar lymphadenopathy. A case of several bilateral, round, excavated opacities and 1 subtracheal adenopathy was reported by David et al [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Case of Secondary Syphilis with Mucocutaneous, Articular, and Pulmonary Involvement in a 74-Year-Old Moroccan Man

2022

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Patient: Male, 74-year-old Final Diagnosis: Secondary syphilis Symptoms: Knee pain Medication:— Clinical Procedure: — Specialty: Rheumatology Objective: Challenging differential diagnosis Background: Syphilis is a sexually transmitted infection (STI) caused by Treponema pallidum . If untreated, primary syphilis can progress to secondary syphilis, which has a characteristic rash and diverse systemic features. This report is of a case of secondary syphilis with mucocutaneous, articular, and pulmonary involvement. Case Report: A 74-year-old Moroccan man presented with an 8-week history of bilateral knee pain and swelling. On examination, he had bilateral knee effusions. Articular puncture brought an inflammatory fluid with a significant presence of white blood cells. Inflammatory markers were elevated. X-rays of both knees showed bilateral osteoarthritis with intra-articular calcification in the left knee. Nonsteroidal anti-inflammatory drugs and colchicine were prescribed, but were ineffective. A closer clinical examination of the patient revealed pigmented papules on the palms, soles, oral mucosa, trunk, and genitals. Treponema pallidum hemagglutination assay and Venereal Disease Research Laboratory results were positive in the blood (titers 1: 32) and joint fluid. A computed tomography scan of the chest revealed a focal opacity in the lateral basal segment of the right lung. The diagnosis of secondary syphilis with mucocutaneous, articular, and pulmonary involvement was made. The evolution was favorable after a single intramuscular injection of benzathine-penicillin. Conclusions: Arthritis, mucocutaneous involvement, and lung lesions can be manifestations of secondary syphilis. A detailed anamnesis, clinical examination, serology, and imaging techniques are the pillars of diagnosing this condition.

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“…34 Tendo em vista que este assunto deve ser encarado com a mesma seriedade com que são tratados outros aspectos de envelhecimento, faz-se necessário que as informações sobre prevenção, proteção, entre outras, tenham visibilidade e alcancem aos familiares, cuidadores e, principalmente, os próprios idosos, viabilizando que o envelhecer seja compatível com uma boa qualidade de vida. 39 Segundo dados publicados em 2016 pelo Ministério da Saúde o crescimento da infecção por sífilis em pacientes acimas de 50 anos está em grande expansão no Brasil. Em 2010 foram notificados 233 casos de sífilis adquirida em pacientes de 50 anos ou mais, logo em 2015 já foram registrados 12.973 casos e em 2016, até a data de 30 de junho já tinham sido notificados 4.746 casos, representando 18,1% do total dos casos até o seguinte momento.…”

Section: Conclusãounclassified

Sífilis Adquirida: Uma Revisão Epidemiológica Dos Casos Em Adultos E Idosos No Município De Porto Alegre/Rs

Mahmud

Clerici

Santos

et al. 2019

Rev Epidemiol Control Infect

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Justificativa e Objetivos:Sabe-se que a sífilis adquirida, no cenário epidemiológico gaúcho, configura-se como doença de extrema importância devido a sua alta prevalência e ascensão. A partir disso, o seguinte trabalho visa revisar as medidas utilizadas na assistência dos pacientes adultos e idosos com diagnóstico de sífilis adquirida e sua epidemiologia no município de Porto Alegre/RS. Conteúdo: Segundo dados publicados em 2016 pelo Ministério da Saúde, o crescimento da infecção por sífilis em indivíduos adultos e idosos está em grande expansão no Brasil. Através das conquistas pelos idosos nas últimas décadas, o prolongamento da vida sexual é ponto merecedor de destaque, além do incentivo à socialização e a falta de informação sobre saúde sexual. Conclusão:As infecções sexualmente transmis-síveis crescem nestes dois públicos e necessita-se medidas preventivas mais efetivas no âmbito da saúde pública. Descritores: Sífilis. Doenças Transmissíveis. Saúde Pública. Doenças infecciosas

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Secondary pulmonary syphilis: Case report and review of literature

Cited by 12 publications

References 23 publications

An Unusual Case of Syphilis With Pulmonary Involvement

An Unusual Case of Syphilis With Pulmonary Involvement

Case of Secondary Syphilis with Mucocutaneous, Articular, and Pulmonary Involvement in a 74-Year-Old Moroccan Man

Sífilis Adquirida: Uma Revisão Epidemiológica Dos Casos Em Adultos E Idosos No Município De Porto Alegre/Rs

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