1985
DOI: 10.1097/00006324-198507000-00008
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Sector Pupil Dilation with Phenylephrine and Tropicamide

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Cited by 13 publications
(4 citation statements)
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“…Cyclopentolate and tropicamide both neutralize the iris' sphincter muscle, which consists of fibers that are arranged in a circular fashion and typically contract uniformly to constrict the pupil. When an appropriate agent inhibits the sphincter fibers, they relax and, as suggested by Chang et al, 29 collectively move after a short period of time to produce a symmetric dilation of the pupil. Neo-Synephrine, however, acts on the dilator muscle of the iris, which consists of several radiating fiber strands that can contract independently to dilate the iris.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Cyclopentolate and tropicamide both neutralize the iris' sphincter muscle, which consists of fibers that are arranged in a circular fashion and typically contract uniformly to constrict the pupil. When an appropriate agent inhibits the sphincter fibers, they relax and, as suggested by Chang et al, 29 collectively move after a short period of time to produce a symmetric dilation of the pupil. Neo-Synephrine, however, acts on the dilator muscle of the iris, which consists of several radiating fiber strands that can contract independently to dilate the iris.…”
Section: Discussionmentioning
confidence: 99%
“…22 As shown in Figure 4, the iris thinned more in the inferonasal direction after being dilated with Neo-Synephrine 2.5% in most eyes, accounting for the inferonasal shift in pupil center location with dilation. Chang et al 29 found that phenylephrine 2.5% produced an uneven dilation of the pupil, particularly in the vertical direction, while tropicamide 1% yielded a symmetrical dilation.…”
Section: Discussionmentioning
confidence: 99%
“…8, April mydriatic effect of this particular drug on the pupil is sufficiently persistent that this factor was of minimal importance, its duration being over 180 min, with maximum dilation occurring some 15-20 min after instillation (Ward and Charman, 1986). Although it has been suggested that sector dilation of the pupil can be obtained using weak mydriatics (Chang, McCan and Hitchcock, 1985), this is unlikely to occur with 1 % cyclopen tolate.…”
Section: Methodsmentioning
confidence: 96%
“…Similarly, any sectoral differences in the drug effect might result in slight variations in lens centration and tilt, and hence coma. This possibility is not unreasonable, since sectoral differences have been observed using Scheimpflug photography when the pupil was dilated pharmacologically (Chang et al. , 1985).…”
Section: Discussionmentioning
confidence: 99%