Lung rehabilitation is safe and feasible, and it has positive benefits in weaning the machine as soon as possible, shortening the time of hospitalization and improving the prognosis of children with mechanical ventilation. However, at present, the traditional medical concept is deep-rooted, and doctors' understanding of early rehabilitation is inadequate. It is necessary to make in-depth exploration in the relevant guidelines and expert consensus to formulate standardized early rehabilitation diagnosis and treatment procedures and standards for mechanically ventilated children. In the paper, a structured graded lung rehabilitation program is constructed for children with mechanical ventilation to improve their respiratory function, shorten the time of mechanical ventilation and pediatric intensive care unit (PICU) hospitalization, and reduce their anxiety, based on the principal component analysis of functional pneumonia data. Scientific evaluation and dynamic monitoring ensure the safety of the implementation of the program and promote the prognosis and prognosis of the disease. The proposed lung rehabilitation program provides a reference basis for the formulation of lung rehabilitation guidelines for children with mechanical ventilation. And It has important reference significance for clinical pulmonary rehabilitation to alleviate the concerns of clinicians and lay the foundation for the large-scale promotion of early lung rehabilitation.