Selected Topics in Optical Coherence Tomography

Liu, Gangjun

doi:10.5772/1259

Cited by 4 publications

References 125 publications

(207 reference statements)

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Microvascular imaging: techniques and opportunities for clinical physiological measurements

Allen¹,

Howell²

2014

Physiol. Meas.

166

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The microvasculature presents a particular challenge in physiological measurement because the vessel structure is spatially inhomogeneous and perfusion can exhibit high variability over time. This review describes, with a clinical focus, the wide variety of methods now available for imaging of the microvasculature and their key applications. Laser Doppler perfusion imaging and laser speckle contrast imaging are established, commercially-available techniques for determining microvascular perfusion, with proven clinical utility for applications such as burn-depth assessment. Nailfold capillaroscopy is also commercially available, with significant published literature that supports its use for detecting microangiopathy secondary to specific connective tissue diseases in patients with Raynaud's phenomenon. Infrared thermography measures skin temperature and not perfusion directly, and it has only gained acceptance for some surgical and peripheral microvascular applications. Other emerging technologies including imaging photoplethysmography, optical coherence tomography, photoacoustic tomography, hyperspectral imaging, and tissue viability imaging are also described to show their potential as techniques that could become established tools for clinical microvascular assessment. Growing interest in the microcirculation has helped drive the rapid development in perfusion imaging of the microvessels, bringing exciting opportunities in microvascular research.

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Microvascular imaging: techniques and opportunities for clinical physiological measurements

Allen¹,

Howell²

2014

Physiol. Meas.

166

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From Doppler to speckle variance measurements in optical coherence tomography

Podoleanu

Caujolle

Marques

et al. 2018

Seventh International Conference on Lasers in Medicine

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Study of the retina macular region microvascular bed parameters in healthy people of the older age group according to optical coherence tomography with angiography function

Lyskin,

Volodin,

Makarenko

2024

Kazan Med J

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BACKGROUND: To date, there is insufficient data on normal blood flow indicators in the retinal choroid plexuses in healthy people of the older age group. AIM: To create a normative basis for average indicators of vessel density in the superficial and deep plexuses of the retina, parameters of the foveal avascular zone and retinal thickness in the macular region in healthy people of the older age group according to optical coherence tomography with angiography. MATERIAL AND METHODS: The retrospective study included 73 people (146 eyes) aged from 58 to 79 years with preserved visual functions and somatic parameters corresponding to the age norm. Optical coherence tomography with angiography function analyzed the density of vessels in the superficial and deep retinal plexuses, the area and perimeter of the foveal avascular zone, the density of vessels in the area up to 300 μm from the foveal avascular zone, and the thickness of the retina. Statistical processing of the data was performed in MS Office Excel 2016. The data was presented in the format M±σ, where M was the average value of the indicator, σ was the standard deviation. RESULTS: In the study group, the overall average retinal thickness in the macular area was 279.9±14.8 µm. The overall average density of vessels of the superficial retinal plexus in the macular zone of the retina was 48.7±2.5%. The overall average density of vessels in the deep retinal plexus in the macular area was 51.9±3.7%. The area of the foveal avascular zone in healthy people was on average 0.322±0.123 mm2; the density of vessels within 300 µm from the foveal avascular zone was 53.8±3.3%. CONCLUSION: The age-related physiological norm for blood flow indicators in the retinal choroid plexuses in healthy people of the older age group has been established.

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Selected Topics in Optical Coherence Tomography

Abstract: where he is currently an assistant specialist. He has authored or co-authored more than 50 papers in peer-reviewed scientific journals and conference proceedings. His research interests are in the area of biophotonics.

Cited by 4 publications

References 125 publications

Microvascular imaging: techniques and opportunities for clinical physiological measurements

Microvascular imaging: techniques and opportunities for clinical physiological measurements

From Doppler to speckle variance measurements in optical coherence tomography

Study of the retina macular region microvascular bed parameters in healthy people of the older age group according to optical coherence tomography with angiography function

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