Selected zinc metabolism parameters in women with arterial hypotension

Abstract

In the present study, differences between selected zinc parameters in healthy women and arterial hypotension patients were compared. The patients had baseline systolic blood pressure that did not surpass 100 mm Hg. During the orthostatic test, a decrease of over 20 mm Hg was seen and the patients reported dizziness, limpness, and palpitations. The patients had higher levels of lymphocyte zinc than those of the controls and exhibited a positive correlation between serum zinc and the ouabain-dependent zinc efflux from lymphocytes (r = 0.49), and, in turn, this efflux was negatively correlated to the serum aldosterone level (r = -0.35). Except for the differences in their systolic blood pressure and lymphocyte zinc, none of the tested zinc metabolism parameters showed significant differences between the patients and the controls. As in arterial hypertension, the obtained results indicate that zinc plays a significant role in regulation of arterial blood pressure.

Zinc deficiency and cellular oxidative stress: prognostic implications in cardiovascular diseases

“…Loss of zinc homeostasis can be both the cause and effect of hypertension. A large amount of data from both clinical and animal studies has confirmed the altered distribution of zinc between the extracellular and intracellular spaces as well as tissue distribution in arterial hypertension 62 . Earlier studies found that there was a negative correlation between arterial blood pressure and zinc content in the serum and higher zinc concentration in the red blood cells in patients suffering from primary arterial hypertension.…”

Fabrication and Properties of Zn-3Mg-1Ti Alloy as a Potential Biodegradable Implant Material

“…In addition, Zn can also induce Ca-P deposition, stimulate bone formation, growth, and mineralization. [ 16 , 17 , 18 , 19 , 20 ]. As a biodegradable material with good biocompatibility and an acceptable degradation rate, pure zinc has been intensively investigated by researchers.…”