Selecting for heat tolerance

Glucose Metabolism and Dynamics of Facilitative Glucose Transporters (GLUTs) under the Influence of Heat Stress in Dairy Cattle

“…The identification of genetic markers and quantitative trait loci related to improvements in energy status and production under heat stress will surely form the basis of genomic selection for thermal tolerance [11]. The identification of such valuable markers requires certain appropriate phenotypes so that accurate genetic effects can be predicted [102]. In the above discussion, we referenced some important studies which have predicted the differential level of expression of certain metabolites, amino acids, and hormones [36,53,103] that can be regularly recorded as phenotypes for the individual energetic metabolic status among dairy cows.…”

“…Besides convenient milking line measurements, milk temperature measurement as the reliable substitute for the individual dairy cow body temperature offers additional benefits in this regard [104]. Combining physiological manifestations of dairy cattle under heat stress, novel relevant phenotype measurements [105], and the integration of molecular techniques [102] could make the journey towards thermo-tolerance more achievable.…”

“…Crossbreeding with thermo-tolerant animals, preferably within the breed, is a way forward in this context [132,133]. The basic idea of thermo-tolerance breeding includes identification of thermally adapted cows [105], with due consideration to the relevant phenotype [102], and thus, having thermo-tolerant cows with good adaptability towards the challenge of heat stress conditions [94]. The detection of genetic markers associated with improved energy metabolism and production would provide the basis for the thermo-tolerance capability of dairy cattle [11] and help in understanding the biological mechanisms of thermo-tolerance [102], such as differential expression of certain genes, metabolites, amino acids, and hormones [53,61].…”

“…The basic idea of thermo-tolerance breeding includes identification of thermally adapted cows [105], with due consideration to the relevant phenotype [102], and thus, having thermo-tolerant cows with good adaptability towards the challenge of heat stress conditions [94]. The detection of genetic markers associated with improved energy metabolism and production would provide the basis for the thermo-tolerance capability of dairy cattle [11] and help in understanding the biological mechanisms of thermo-tolerance [102], such as differential expression of certain genes, metabolites, amino acids, and hormones [53,61]. This obtained information can thereby be used for the identification of genes and genomic regions along with associated phenotype measurements responsible for thermo-tolerance, that can be ultimately used in genomic selection [102].…”

Genetic Diversity of the Structure of HSP70 Gene in Kampung Unggul Balitbangtan (KUB), Walik, and Kate Walik Chickens

“…Many reports have proved that frizzle (F) and naked neck (Na) are well known as major marker genes affecting heat stress tolerance, resistant to diseases, and better immune system (Fathi et al 2013(Fathi et al , 2014. Several tropical countries have introduced these genes in breeding programs to improve performance and adaptability of chickens to hot ambient temperatures (Fathi et al 2013(Fathi et al , 2014Carabańo et al 2019). Recently, supplementation of vitamin and mineral are used as antioxidants to reduce the negative effects of heat stress (Rayani et al 2017;Mohamed et al 2019).…”