Selective magnetic solid‐phase extraction of amide herbicides from fish samples coupled with ultra‐high‐performance liquid chromatography with tandem mass spectrometry

Abstract

An efficient magnetic dummy template molecularly imprinted polymer nanocomposite was prepared using multi‐walled carbon nanotubes as a support and metolachlor deschloro as a dummy template. The obtained nanocomposites were characterized using Fourier transform infrared spectroscopy, vibrating sample magnetometry, scanning electron microscopy, and transmission electron microscopy. The adsorption performance of the obtained nanocomposites was evaluated through binding experiments, including static adsorption, kinetic adsorption, and selective recognition studies. The obtained nanocomposites were successfully applied as selective sorbents for the magnetic solid‐phase extraction of seven amide herbicides (alachlor, acetochlor, pretilachlor, butachlor, metolachlor, diethatyl ethyl, and dimethachlor) coupled with liquid chromatography‐tandem mass spectrometry from fish samples. Under the optimized conditions, the limit of detection was 0.01–0.1 μg/kg. The obtained recoveries of the amide herbicides from the fish samples were in the range of 88.0 to 102.1% with a relative standard deviation of less than 7.5%. This method, which eliminated the effect of template leakage on qualitative and quantitative analysis was found to be superior to the methods reported in the literature. The results indicated that it could be successfully applied to analyze amide herbicides in fish samples with satisfactory recoveries.

Application of solid‐phase extraction: High‐resolution mass spectrometry analysis strategy in the characterization and quantification of amide herbicides in aquatic products

“…The results obtained from a comparison of the SPE-UPLC-QTOF method with other procedures used for the determination of amide herbicides in fish samples are given in Table 4 [35][36][37][38][39][40][41]. With the exception of molecular imprinting, the QTOF-based method gave similar values for the LOD, LOQ, and recovery.…”

Development of a MOF-based SPE method combined with GC–MS for simultaneous determination of alachlor, acetochlor and pretilachlor in field soil

“…After the composition of eluent was selected, effects of three main factors, sample pH, NaCl addition and eluent volume, were also investigated. The eluent volume (A) was assessed at three levels (20, 30 and 50 mL), the sample pH (B) at four levels (3,5,7,9), and the NaCl (C) at three levels (0.0, 5 and 10% (w/v)). Table 2 showed the results for the multifactor ANOVA study.…”

“…Amide herbicides are a sort of herbicides widely used in production of corn, peanut, soybean, cotton and other crops, which has the advantages of wide weeding spectrum, outstanding effect, and low cost (Qu, et al 2017;Zhao, et al 2009). However, most amide herbicides, especially alachlor and acetochlor, are carcinogenic, teratogenic and sterile (Gao, et al 2022a). Furthermore, amide herbicides residual in the soil could damage crops (Yang, et al 2021) and affect adjacent systems, such as sh, water bird and other aquatic animals (Qu, et al 2017) by water cycle system.…”

A Sensitive and Specific Monoclonal Antibody Based Enzyme-Linked Immunosorbent Assay for the Rapid Detection of Pretilachlor in Grains and the Environment

“…The limit of detection for both methods ranged from 0.01 to 10 μg/L [ 14 , 15 ]. Gao et al established a high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method for the determination of PR in fish with a detection limit of 0.01~0.1 μg/kg [ 16 ]. These instrumental assays offer the advantage of high sensitivity and accuracy; however, the market is also in need of immunological rapid assay technologies to enable the rapid detection of PR residue.…”