Selectivity tunable iron nanoparticles from lignocellulosic components for the reductive amination of carbonyl compounds towards switchable products

Abstract

Varied sorts of functional amines have been well synthesized by the reductive amination of carbonyl compounds for high-value pharmaceuticals, but often suffers from problems of separated processes and low efficiency....

General synthesis of secondary imines via reductive coupling of carbonyl and nitro compounds employing a reusable cobalt catalyst

“…As shown in Table 2, a broad range of aromatic/hetero-aromatic, alicyclic and aliphatic aldehydes were aminated successfully, affording the corresponding secondary imines in yields of 71–97% (Table 2, entries 1–20), which was comparable or even superior to the reported methods (Table S7, ESI†). 9,10,28,29 The electronic properties of the substituted groups showed no obvious effect on the activity of the substituted benzyl aldehydes. Meanwhile, no steric hindrance was observed for the ortho -substituent aromatic aldehydes (Table 2, entries 3, 10 & 12).…”

“…More importantly, Co@NC-800 was also effective for the reductive amination of inert alicyclic and aliphatic aldehydes, which was challenging (Table 2, entries 17–20). 10,28,29…”