Selenium and clarithromycin loaded PLA-GO composite wound dressings by electrospinning method

A comprehensive review on the applications of carbon-based nanostructures in wound healing: from antibacterial aspects to cell growth stimulation

“…has Additionally, the fibers exhibited a high drug loading capacity, chemical stability and low cytotoxicity. 60 In another report, polyvinyl alcohol with an increasing loading of GO and aspirin-adsorbed GO were wet-spun into continuous composite fibers and introduced as wound dressings and wound sutures. The crystalline nature of the GO liquid improved the electrical, mechanical and thermal properties and increased the length of the composite fibers.…”

Local Drug Delivery Strategies towards Wound Healing

“…Another antimicrobial agent that penetrates burned tissue is cerium nitrate. It has a wide range of activity against Gram-positive and Gram-negative bacteria, as well as fungal species, and is highly effective when used in conjunction with silver sulphadiazine [ 56 ]. Povidone iodine is fully hazardous to keratinocytes and fibroblasts at concentrations greater than 0.004 and 0.05%, respectively [ 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 ].…”

“…Effective antiseptics for local wounds include polyhexanide and octenidine dihydrochloride. Nitrofuran and natrium fusidate are other antibacterial substances ( Table 1 ) [ 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 ].…”

“…Activated charcoal dressings are frequently used in malodorous wounds; however, odour control has not received as much attention in the literature as wound healing has. According to current clinical experiences, it is evident that these dressings can reduce wound odour, but there are not any hard facts on just charcoal ingredients [ 56 , 57 , 58 ].…”

An In Vitro Study of Antibacterial Properties of Electrospun Hypericum perforatum Oil-Loaded Poly(lactic Acid) Nonwovens for Potential Biomedical Applications

“…Researchers have been worked about the development antibacterial PLA-based electrospun materials using chitosan and silver [43], thymol [44], propolis [45], silver and vitamin E [46], copaiba (Copaifera sp.) oil [47], tetracycline hydrochloride and chitosan [48], cinnamon essential oil [49], thymoquinone [50], tea tree and manuka oil [51], carvacrol [52], clary sage and black pepper [53], terpinen-4-ol [54], epidermal growth factor [55], quercetin [56], Nigella sativa herbal extract [57], Eucalyptus essential oil [58], silver diclofenac complex [59], chitosan, black pepper essential oil and limonene [60], selenium and clarithromycin [61], cefazolin [62], silver nanoparticles [63], zinc oxide [64], thyme essential oil [65], zenian (Carum copticum) essential oil [66], birch bark triterpene extract [67], Capparis spinosa L. extracts [68], Plumbago europaea plant extract [69], curcumin [70], babassu oil [71], and cypress (Cupressus sempervirens L.) essential oil [72].…”