Selenium Metabolism in Cattle: Maternal Transfer of Selenium to Newborn Calves at Different Selenium Concentrations in Dams

Pavlata, L.; Prášek, Jiří; Podhorský, A.; Pechová, Alena; Haloun, T.

doi:10.2754/avb200372040639

Cited by 35 publications

(34 citation statements)

References 26 publications

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“…In one herd only, slightly lower values in calves were found at the GSH-Px activity above 600 µkat/l. This finding is in agreement with our previous results when we reported a very close correlation between Se concentrations and GSH-Px activity in the blood of newborn calves and their dams (r = 0.91 and 0.93, respectively) (Pavlata et al, 2003). Relatively good results were obtained in cows and their calves, when Se deficiencies were found in 20 and 25% of farms, respectively.…”

Section: Discussionsupporting

confidence: 93%

“…Our evaluation of the Se status of cows and their calves has confirmed that the Se status in calves is very similar to that of cows, and if an adequate (or, alternatively, deficient) Se status is found in one of the two groups, it may be assumed that it also applies to the other group (Pavlata et al, 2003(Pavlata et al, , 2004b. Although statistically significant differences between GSH-Px activities in calves and their dams were found on 4 farms, the differences could not have caused a fundamentally wrong interpretation of the Se status, i.e.…”

Section: Discussionsupporting

confidence: 67%

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Differences in the occurrence of selenium, copper and zinc deficiencies in dairy cows, calves, heifers and bulls

Pavlata¹,

Podhorský²,

Pechová³

et al. 2005

Vet. Med. - Czech

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This study was conducted to evaluate the mineral status of various bovine categories reared on the same farm, and to monitor the quality of their mineral nutrition in this way. Blood samples were collected on 20 farms in various regions of the CzechRepublicto diagnose the selenium (Se), copper (Cu) and zinc (Zn) status of dairy cows, calves, heifers and bulls. Blood samples were collected from 5 dairy cows and their calves, 5 heifers and, whenever possible, also from 5 bullocks (10 farms). To assess the Cu and Zn status of the cattle, blood serum concentrations of the elements were determined by flame AAS. The Se status assessment was based on the glutathione peroxidase (GSH-Px) activity in whole blood. Dairy cows and calves showed the higher GSH-Px activity in comparison with heifers and bulls (P < 0.001). Overall mean GSH-Px activity in the blood of dairy cows, calves, heifers and bulls was 720.47 ± 174.47 µkat/l, 688.34 ± 204.12 µkat/l, 555.69 ± 318.36 µkat/l and 516.17 ± 214.70 µkat/l, respectively. Se deficiency was diagnosed in 23% of the examined dairy cows (20% herds), 31% calves (25% herds), 51% heifers (50% herds) and in 58% of bulls (50% herds). Dairy cows showed lower Zn and higher Cu concentrations in comparison with the other categories (P < 0.001). Mean Zn concentrations in blood serum of dairy cows, calves, heifers and bulls were 12.21 ± 3.19 µmol/l, 18.91 ± 5.78 µmol/l, 17.80 ± 2.76 µmol/l and 16.69 ± 3.08 µmol/l, respectively. Zn deficiency was diagnosed in 41% of the examined dairy cows (45% herds) and 13% of bulls (10% herds). None of the calf or heifer herds was classified as Zn deficient when Zn deficiency was found in only 9% of calves and 1% of the examined heifers. Mean Cu concentrations in blood serum of dairy cows, calves, heifers and bulls were 13.62 ± 2.62 µmol/l, 10.18 ± 3.22 µmol/l, 10.96 ± 2.52 µmol/l and 11.18 ± 2.40 µmol/l, respectively. Cu deficiency was diagnosed in 28% of the examined dairy cows (20% herds), 70% of calves (80% herds), 65% of heifers (75% herds) and 70% of bulls (60% herds). Deficiency of at least one of the microelements monitored was diagnosed on all investigated farms.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 67%

Differences in the occurrence of selenium, copper and zinc deficiencies in dairy cows, calves, heifers and bulls

Pavlata¹,

Podhorský²,

Pechová³

et al. 2005

Vet. Med. - Czech

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“…This is in contrast to results which have been acquired in cattle. Pavlata et al (2003) found similar levels of selenium in the blood of cows and their calves. Kincaid and Hodgson (1989) also found, in cows with access to selenium-containing lick, that their calves had approximately identical levels of selenium in whole blood as their mothers on the day of delivery.…”

Section: Resultsmentioning

confidence: 68%

“…Levels of microelements in newborns ruminants and their mothers have not yet been studied extensively and thus available information is limited. Most publications on this topic monitor the levels of selenium in cattle (Koller et al, 1984;Kincaid and Hodgson, 1989;Pavlata et al, 2003), or sheep (Langlands et al, 1991). For this reason we monitored the levels of selenium and activity of glutathione peroxidase in goats and their kids.…”

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confidence: 99%

Selenium metabolism in goats - maternal transfer of selenium to newborn kids

Mišurová¹,

Pavlata²,

Pechová³

et al. 2009

Vet. Med.

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AbStrAct:The aim of our study was to compare the concentration of selenium (Se) and the activity of glutathione peroxidase (GSH-Px) in the whole blood of goats and their newborn kids. The experiment involved 25 gravid, clinically healthy goats of the white shorthaired breed. On the day of delivery, we took whole blood from the mother and her newborn kid before the kid drank the first colostrum. In mothers, the measured average concentration of Se in whole blood was 149.60 ± 45.01 μg/l, the average concentration of Se in kids was 87.91 ± 29.66 μg/l. Average activity of GSH-Px in the blood of mothers was 938.46 ± 341.09 μkat/l, and in the blood of kids 658.20 ± 339.13 μkat/l. Regression and correlation analysis produced regression line formulas and correlation coefficients that revealed a close, statistically significant relation (p < 0.01) between the concentration of Se in the blood of mothers and their kids and the activity of GSH-Px in mothers and their kids. The relation between the concentration of Se in the blood (µg/l) of mothers and kids was y = 0.484x + 15.55; r = 0.73, the relation between the activity of GSH-Px in blood (µkat/l) of mothers and their kids was y = 0.809x -101.27; r = 0.80. The concentration of Se and activity of GSH-Px was lower in newborn kids than in their mothers, reaching approximately 60-70% of the mother's levels. The relation between the concentration of Se and activity of GSH-Px in the blood of goats was y = 4.23x + 276.31; r = 0.64 (p < 0.01) and the relation between the concentration of Se and the activity of GSH-Px in the blood of kids was y = 6.556x + 64.70; r = 0.83 (p < 0.01). It follows that a Se concentration of 100 μg/l corresponds to a GSH-Px activity of 699.51 μkat/l in the blood of mothers and 720.34 μkat/l in the blood of kids. The results show the need to provide for a sufficient Se saturation of goats with a view to preventing Se deficiency in kids and that the Se concentration in the blood of newborn kids is physiologically about 40% lower in comparison with the Se concentration in the blood of their mothers. This should be taken into account when interpreting the results and assessing the reference values of Se concentration in the blood of kids.

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“…This work goes out from a part of an experiment realised in a framework of an investigation of selenium metabolism in the maternal transfer of selenium to newborn calves (Pavlata et al, 2003). The method in this work is expanded and results are evaluated from the wiev of an influence of selenium and vitamin E on selected metabolic parameters, colostrum quality and state of health.…”

Section: Methodsmentioning

confidence: 99%

Influence of parenteral administration of selenium and vitamin E during pregnancy on selected metabolic parameters and colostrum quality in dairy cows at parturition

Pavlata¹,

Prášek²,

Filípek³

et al. 2004

Vet. Med. - Czech

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The aim of the present work was to study the influence of different dose of parenteral administration selenium and vitamin E in dairy cows prior to parturition on selected metabolic parameters and colostrum quality. A total of 19 dairy cows from a farm with selenium deficiency were included in the study. The cows were divided in 3 groups (C, E1, and E2). In group E1 a product containing selenium and vitamin E (Selevit inj. a.u.v.) was administered IM four weeks prior to the expected date of parturition. In group E2 the same product was administered twice, eight and four weeks prior to parturition. Group C consisted of control animals to which no product was administered. On the day of parturition samples of blood and first colostrum were collected for laboratory examination. Concentrations of selenium were determined in blood andthat ofvitamin E, thyroid hormones (T3 and T4) and activities of enzymes detecting muscular damage (CK, AST, LD) were determined in serum. Colostrum was analysed to determine the concentrations of selenium, vitamin E, immunoglobulins, as well as to determine its density. The occurrence of the disease during the first month after parturition was evaluated in all groups. Higher concentrations of selenium and vitamin E were found in the samples (experimental groups E1 and E2) collected on the day of parturition. Group E2 showed a significantly (p < 0.05) higher T3 concentration compared to groups C and E1 (3.05 ± 0.42 nmol/l vs 1.88 ± 0.71 and 1.81 ± 0.30 nmol/l, respectively). The same pattern was confirmed for immunoglobulins concentrations in colostrum (34.08 ± 5.93 U ZST vs 22.87 ± 5.41 and 21.38 ± 8.33 U ZST, respectively). Compared to group C, cows in group E2 also showed significantly (p < 0.05) higher concentrations of selenium in colostrum (45.43 ± 10.56 vs 29.29 ± 8.42 µg/l). The administration of selenium and vitamin E did not influence other parameters evaluated in the study. During the first 30 days of the postpartum period a trend of lower occurrence of mastitis was observed in group E2 compared to both group C and E1 (no case of mastitis compared to 5 and 4 cases of treated mastitis, respectively).

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Selenium Metabolism in Cattle: Maternal Transfer of Selenium to Newborn Calves at Different Selenium Concentrations in Dams

Cited by 35 publications

References 26 publications

Differences in the occurrence of selenium, copper and zinc deficiencies in dairy cows, calves, heifers and bulls

Differences in the occurrence of selenium, copper and zinc deficiencies in dairy cows, calves, heifers and bulls

Selenium metabolism in goats - maternal transfer of selenium to newborn kids

Influence of parenteral administration of selenium and vitamin E during pregnancy on selected metabolic parameters and colostrum quality in dairy cows at parturition

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