Selenium nanoparticle as a bright promising anti-nanobacterial agent

Sardarabadi, Hadi; Mashreghi, Mansour; Jamialahmadi, Khadijeh; Matin, Maryam Moghaddam; Darroudi, Majid

doi:10.1016/j.micpath.2018.10.026

Cited by 8 publications

(7 citation statements)

References 25 publications

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“…Importantly, intaking low selenium increases the risk of mortality, poor immune function, and cognitive decline. Selenium can penetrate bacteria cells, catalyze the oxidation of intracellular thiols, and generate the singlet oxygen, which further causes the death of bacteria 27 , 28 . Besides bacteria inhibition, selenium doped nanoparticles also show effective anti-cancer properties 29 .…”

Section: Introductionmentioning

confidence: 99%

Nanostructured selenium-doped biphasic calcium phosphate with in situ incorporation of silver for antibacterial applications

Nie

Hou

Wang

et al. 2020

Sci Rep

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Selenium-doped nanostructure has been considered as an attractive approach to enhance the antibacterial activity of calcium phosphate (cap) materials in diverse medical applications. in this study, the selenium-doped biphasic calcium phosphate nanoparticles (SeB-NPs) were first synthesized. Then, silver was in situ incorporated into SeB-NPs to obtain nanostructured composite nanoparticles (Ag SeB-NPs). Both SeB-NPs and Ag SeB-NPs were characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), ultraviolet-visible spectroscopy (UV-Vis), X-ray photoelectron spectroscopy (XPS), and Raman spectra. The results confirmed that the SeO 3 2− was doped at the po 4 3− position and silver nanoparticles were deposited on the surface of SeB-NPs. Next, Transmission Electron Microscopy (TEM) analysis displayed that the prepared Ag SeB-NPs had a needlecluster-like morphology. CCK-8 analysis revealed SeB-NPs and Ag SeB-NPs had good cytocompatibility with osteoblasts. the antibacterial activity of the prepared Ag SeB-NPs was confirmed by using Gramnegative E. coli and Gram-positive S. aureus. The above results manifested the significance of the final Ag SeB-NPs for biomedical applications. Tissue engineering has been widely used in bone graft and dentistry due to a large number of patients require grafting resulting from congenital conditions, trauma, and tumor resection, and so on 1-3. Mineralized tissues, such as bone, tooth enamel, dentin, and cementum, are enriched with significant amounts of ionic substitutions, including sodium, potassium, and carbonate groups. These elements can affect the functionality of related tissues 4,5. Calcium phosphate (CaP) based nanoparticles, including hydroxyapatite (Ca 10 (PO 4) 6 (OH) 2 , HA), β-tricalcium phosphate (Ca 3 (PO 4) 2 , β-TCP), tetracalcium phosphate (Ca 4 (PO 4) 2 O; TTCP), biphasic calcium phosphate (BCP), and so forth, were well-known in implant surgery because of their excellent biocompatibility, biodegradability, and tunable physicochemical properties. Compared to HA or β-TCP, biphasic calcium phosphate (BCP) composed of HA and β-TCP, performed better mechanical properties, higher biological activity, and adjustable degradation rate 6-10. Bacteria attached to the implanted medical devices or scaffold can cause healthcare-associated infections, such as the formation of biofilm, which further results in local inflammation and infection. Therefore, the scaffold with excellent antibacterial properties provides an overwhelming advantage in the clinic stage 11,12. Many metal nanoparticles, such as silver (Ag), zinc oxide (ZnO), and titanium dioxide (TiO 2), performed strong antibacterial properties and low toxicity towards mammalian cells, some of these nanoparticles have been widely applied in a range of areas 13-20. Silver (Ag) is stable in the body fluids and can be used in antibacterial implants due to silver can easily binds to bacterial DNA and RNA, resulting in bacteria death 21. However, the antibacterial effect of nanoparticles was influenced...

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Section: Introductionmentioning

confidence: 99%

Nanostructured selenium-doped biphasic calcium phosphate with in situ incorporation of silver for antibacterial applications

Nie

Hou

Wang

et al. 2020

Sci Rep

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“…Selenium, because of its unique biological function, can protect the kidney from arsenic and cadmium [ 26 , 27 ]. Sardarabadi et al found that selenide nanoparticles had an obvious inhibitory effect on the deposition and aggregation of CaOx crystals using transmission electron microscopy and energy-dispersive X-ray analysis [ 12 ]. In addition, another study also found that compared with astragalus polysaccharides, selenide astragalus polysaccharides had a stronger ability to inhibit the formation of CaOx crystals and protect cells from COM damage [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

“…The inhibitory function of selenium on the occurrence of kidney stones can be found in animal models [ 10 ]. Meanwhile, it has been found that compared with astragalus polysaccharides, selenide astragalus polysaccharides have a stronger ability to inhibit stone formation [ 11 ], and nano-selenium particles have an obvious negative effect on the aggregation and growth of CaOx crystals [ 12 , 13 ]. Studies have found that when oxalate crystals are released from damaged thyroid epithelium and colloids, they can cause a series of inflammatory reactions, oxidative stress, and immune reactions (macrophages around oxalate crystals can be observed) [ 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

Dietary Selenium Intake and Kidney Stones in Old Adults: an Analysis from NHANES 2011 to 2018

Chen

et al. 2022

Biol Trace Elem Res

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The association between dietary selenium intake and kidney stones remains unclear. The purpose of this study was to explore the correlation between dietary selenium intake and kidney stones in older adults. A total of 6669 adults aged ≥ 60 years who had participated in the National Health and Nutrition Examination Survey (NHANES) during 2011–2018 were enrolled in the current study. The correlation between dietary selenium intake and kidney stones was assessed by the logistic regression analysis. Smooth curve fitting was used to explore the potential non-linear relationship and subgroup analyses were further adopted. After adjustment for multiple confounding factors, the odds ratio (OR) with 95% confidence interval (CI) of kidney stones for per standard deviation increment in dietary selenium intake was 0.92 (0.85, 1.00) overall. Compared with the lowest quartile, the ORs (95% CIs) with increasing quartiles were 0.88 (0.71, 1.08), 0.82 (0.66, 1.02), and 0.79 (0.64, 0.97). In addition, smooth curve fitting and stratified analyses showed that there was a non-linear and stable correlation between dietary selenium intake and the occurrence of kidney stones respectively. For adults aged over 60, dietary selenium intake was inversely correlated with kidney stones, and this relationship remained after adjusting for other confounding variables. Further researches are needed to explore the potential mechanism between dietary selenium intake and kidney stones.

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“…Interestingly, nano-Se is more effective than sodium selenite with regard to its anti-coccidial, anti-oxidant, and anti-inflammatory role against coccidiosis induced in the jejunum of mice (Alkhudhayri et al ., 2018). Nano-Se was also shown to restrict the growth of nanobacteria (Sardarabadi et al ., 2019). Therefore, non-selenoprotein action of nano-Se is proven but further research is needed to address the question if both ( via selenoproteins or direct action) mechanisms are responsible for biological effects of nano-Se.…”

Section: Discussionmentioning

confidence: 99%

Food for thought: nano-selenium in poultry nutrition and health

Surai

Kochish

2020

Anim. Health. Res. Rev.

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In recent years, nanoparticles have become a fashionable subject of research due to their sizes, shapes, and unique intrinsic physicochemical properties. In particular for the last 5 years, nano-Se has received tremendous attention in terms of its production, characteristic, and possible application for poultry/animal science and medical sciences. Indeed, Nano-Se is shown to be a potential source of Se for poultry/animal nutrition. However, there is an urgent need to address the questions related to nano-Se absorption, assimilation, and metabolism. It is not clear at present if major biological effects of nano-Se are due to Se-protein synthesis, direct antioxidant/prooxidant effects, or both. It is necessary to understand how metallic nano-Se can be converted into H2Se and further to SeCys to be incorporated into selenoproteins. The aforementioned issues must be resolved before nano-Se finds its way to animal/poultry production as a feed supplement and clearly this subject warrants further investigation.

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Selenium nanoparticle as a bright promising anti-nanobacterial agent

Cited by 8 publications

References 25 publications

Nanostructured selenium-doped biphasic calcium phosphate with in situ incorporation of silver for antibacterial applications

Nanostructured selenium-doped biphasic calcium phosphate with in situ incorporation of silver for antibacterial applications

Dietary Selenium Intake and Kidney Stones in Old Adults: an Analysis from NHANES 2011 to 2018

Food for thought: nano-selenium in poultry nutrition and health

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