Self-assembled cyclodextrin-modified gold nanoparticles on silica beads as stationary phase for chiral liquid chromatography and hydrophilic interaction chromatography

Li, Yuanyuan; Wei, Manman; Chen, Tong; Zhu, Nan; Ma, Yulong

doi:10.1016/j.talanta.2016.07.016

Cited by 24 publications

(7 citation statements)

References 26 publications

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“…Diverse functionalizations of GO sheets are reported in the literature. β-CD-functionalized graphene-based materials are interesting materials being explored when focusing on separating chiral mixtures [78,80]. Other…”

Section: Packed Columnsmentioning

confidence: 99%

Recent Trends in Graphene-Based Sorbents for LC Analysis of Food and Environmental Water Samples

Borsatto

Lanças

2023

Molecules

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This review provides an overview of recent advancements in applying graphene-based materials as sorbents for liquid chromatography (LC) analysis. Graphene-based materials are promising for analytical chemistry, including applications as sorbents in liquid chromatography. These sorbents can be functionalized to produce unique extraction or stationary phases. Additionally, graphene-based sorbents can be supported in various materials and have consequently been applied to produce various devices for sample preparation. Graphene-based sorbents are employed in diverse applications, including food and environmental LC analysis. This review summarizes the application of graphene-based materials in food and environmental water analysis in the last five years (2019 to 2023). Offline and online sample preparation methods, such as dispersive solid phase microextraction, stir bar sorptive extraction, pipette tip solid phase extraction, in-tube solid-phase microextraction, and others, are reviewed. The review also summarizes the application of the columns produced with graphene-based materials in separating food and water components and contaminants. Graphene-based materials have been reported as stationary phases for LC columns. Graphene-based stationary phases have been reported in packed, monolithic, and open tubular columns and have been used in LC and capillary electrochromatography modes.

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Section: Packed Columnsmentioning

confidence: 99%

Recent Trends in Graphene-Based Sorbents for LC Analysis of Food and Environmental Water Samples

Borsatto

Lanças

2023

Molecules

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“…Much stronger interactions were stabilized with the (+)-enantiomers, compared to the (−)-enantiomers, of tryptophan and phenylalanine, and the system was also shown to be highly stable and reusable (Figure 2). Silica spheres were also functionalized on their surface with β-cyclodextrin-capped Au NPs (about 60 nm in diameter) by Li and colleagues, and they were used as chiral selectors for the enantioseparation of several chiral pesticides and drugs by HPLC [27]. The presence of Au NPs improved the overall efficiency of the system compared to traditional β-CD-modified silica column and could be easily applied to the separation of additional racemic mixtures.…”

Section: Enantioselective Recognitionmentioning

confidence: 99%

Chirality at the Nanoparticle Surface: Functionalization and Applications

Zafar

Ragusa

2020

Applied Sciences

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Chiral molecules, such as amino acids and carbohydrates, are the building blocks of nature. As a consequence, most natural supramolecular structures, such as enzymes and receptors, are able to distinguish among different orientations in space of functional groups, and enantiomers of chiral drugs usually have different pharmacokinetic properties and physiological effects. In this regard, the ability to recognize a single enantiomer from a racemic mixture is of paramount importance. Alternatively, the capacity to synthetize preferentially one enantiomer over another through a catalytic process can eliminate (or at least simplify) the subsequent isolation of only one enantiomer. The advent of nanotechnology has led to noteworthy improvements in many fields, from material science to nanomedicine. Similarly, nanoparticles functionalized with chiral molecules have been exploited in several fields. In this review, we report the recent advances of the use of chiral nanoparticles grouped in four major areas, i.e., enantioselective recognition, asymmetric catalysis, biosensing, and biomedicine.

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“…Nonetheless, although it is highly difficult to compare directly the separation resolution between different analytes and columns, the effectiveness of each strategy is evident whereby in optimised conditions (i. e. pH, buffer concentrations, applied voltages, selected analyte, etc.) the separation resolutions are often well above 2.0, sometimes reaching above 4.0 . Furthermore, within the vast majority of listed published articles, the authors frequently analyse the stability of prepared columns and techniques extensively, along with adjustments to the methods, including changes to the polarity and pH of the mobile phase, for more in‐depth analysis of interactions and enantioseparation.…”

Section: Cyclodextrin Functionalised Nanomaterials In Chiral Recognitionmentioning

confidence: 99%

“…Benzoin, benzoin methyl ether, benzoin ethyl ester, 6,6'-dibromo-1,1'bi-2-napthol, trans-stilbene oxide, flavanone, and 6-hydroxyflavanone HPLC[55] Au NPs on porous silica spheres Fenthion, chlorpyrifos, chlorpyrifosÀ methyl, diazinon, fenchlorpyos, flavanone, propranolol, and equol, 6-hydroxyflavanone RP-LC[59] …”

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confidence: 99%

Cyclodextrin‐Functionalised Nanomaterials for Enantiomeric Recognition

Hobbs

Řezanka

2020

ChemPlusChem

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which are glucose-based cyclic oligosaccharides, are materials that can act inherently as chiral selectors, with many reports of the application of cyclodextrins in enantioseparation. However, many studies have encountered the problem of insufficient enantioselective performance of the chiral selector. One of the main reasons is due to low surface concertation's, whereby interaction between the chiral selector and analyte usually occurs at a surface. Thus, scientists have been trying for the last two decades to overcome this problem, with the incorporation of nanomaterials being promising as they possess a large surface area which allows for the accommodation of a higher concentration of the chiral selectors. Herein, we outline nanomaterial-cyclodextrin conjugates that work in tandem to achieve or enhance enantioselectivity through various methods such as chromatography, adsorption, and removal using magnetic nanoparticles, or enantiorecognition using electrochemical techniques.

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Self-assembled cyclodextrin-modified gold nanoparticles on silica beads as stationary phase for chiral liquid chromatography and hydrophilic interaction chromatography

Cited by 24 publications

References 26 publications

Recent Trends in Graphene-Based Sorbents for LC Analysis of Food and Environmental Water Samples

Recent Trends in Graphene-Based Sorbents for LC Analysis of Food and Environmental Water Samples

Chirality at the Nanoparticle Surface: Functionalization and Applications

Cyclodextrin‐Functionalised Nanomaterials for Enantiomeric Recognition

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