Self-assembled monolayer for toxicant detection using nucleic acid sensor based on surface plasmon resonance technique

Self-assembled monolayers are a unique class of nanostructured materials, with properties determined by their molecular lattice structures, as well as the interfaces with their substrates and environments. As with other nanostructured materials, defects and dimensionality play important roles in the physical, chemical, and biological properties of the monolayers. In this review, we discuss monolayer structures ranging from surfaces (two-dimensional) down to single molecules (zero-dimensional), with a focus on applications of each type of structure, and on techniques that enable characterization of monolayer physical properties down to the single-molecule scale.

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“…Several modifications to soft lithography have been developed to address these challenges. 235,244,254,264,265 …”

Section: Molecular Patterning and Its Applicationsmentioning

confidence: 99%

From the bottom up: dimensional control and characterization in molecular monolayers

et al. 2013

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“…Work has also been performed using calf thymus DNA [126,127]. Solanki et al [126] showed the use of both electrochemical (amperometric) and optical (SPR) biosensors whereby a pesticide is complexed with the immobilised double-stranded DNA in their flow-based systems.…”

Section: Advances Using Other Biosensor Approachesmentioning

confidence: 99%

“…Solanki et al [126] showed the use of both electrochemical (amperometric) and optical (SPR) biosensors whereby a pesticide is complexed with the immobilised double-stranded DNA in their flow-based systems. They detected cypermethrin in water (LOD 0.0005 ppm).…”

Section: Advances Using Other Biosensor Approachesmentioning

confidence: 99%

Biosensors for the analysis of microbiological and chemical contaminants in food

2012

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Increases in food production and the ever-present threat of food contamination from microbiological and chemical sources have led the food industry and regulators to pursue rapid, inexpensive methods of analysis to safeguard the health and safety of the consumer. Although sophisticated techniques such as chromatography and spectrometry provide more accurate and conclusive results, screening tests allow a much higher throughput of samples at a lower cost and with less operator training, so larger numbers of samples can be analysed. Biosensors combine a biological recognition element (enzyme, antibody, receptor) with a transducer to produce a measurable signal proportional to the extent of interaction between the recognition element and the analyte. The different uses of the biosensing instrumentation available today are extremely varied, with food analysis as an emerging and growing application. The advantages offered by biosensors over other screening methods such as radioimmunoassay, enzyme-linked immunosorbent assay, fluorescence immunoassay and luminescence immunoassay, with respect to food analysis, include automation, improved reproducibility, speed of analysis and real-time analysis. This article will provide a brief footing in history before reviewing the latest developments in biosensor applications for analysis of food contaminants (January 2007 to December 2010), focusing on the detection of pathogens, toxins, pesticides and veterinary drug residues by biosensors, with emphasis on articles showing data in food matrices. The main areas of development common to these groups of contaminants include multiplexing, the ability to simultaneously analyse a sample for more than one contaminant and portability. Biosensors currently have an important role in food safety; further advances in the technology, reagents and sample handling will surely reinforce this position.

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“…In the electrochemical impedance spectroscopy, the semicircle portion at higher frequencies corresponds to the electron-transfer limited process and the linear portion at lower frequencies may ascribe to diffusion. The semicircle diameter equals the electron-transfer resistance (R et ), which depends on the dielectric and insulating features at the electrode/electrolyte interface [33,34]. Fig.…”

Section: Resultsmentioning

confidence: 99%

Stripping voltammetric detection of mercury(II) based on a surface ion imprinting strategy in electropolymerized microporous poly(2-mercaptobenzothiazole) films modified glassy carbon electrode

Chen

Guo

et al. 2011

Analytica Chimica Acta

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Self-assembled monolayer for toxicant detection using nucleic acid sensor based on surface plasmon resonance technique

Cited by 39 publications

References 54 publications

From the bottom up: dimensional control and characterization in molecular monolayers

From the bottom up: dimensional control and characterization in molecular monolayers

Biosensors for the analysis of microbiological and chemical contaminants in food

Stripping voltammetric detection of mercury(II) based on a surface ion imprinting strategy in electropolymerized microporous poly(2-mercaptobenzothiazole) films modified glassy carbon electrode

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