Self Limiting Postoperative Hyperbilirubinemia in Acute Abdomina L Conditions : A Study at Rims, Kadapa, Andhra Pradesh

Abstract

Self-limiting postoperative hyperbilirubinemia is seen in most of patients who undergo surgery for acute abdominal conditions like acute appendicitis, peritonitis, blunt injury abdomen, penetrating injury abdomen, intestinal obstruction etc. MATERIALS AND METHODS: Prospective study of 200 cases who were operated for acute abdominal conditions from June 2012 to June 2015 were included in the study. RESULTS: Out of 200 patients included in the study around 158 patients had postoperative hyperbilirubinemia which is around 79% of total patients which is significant. CONCLUSION: Postoperative hyperbilirubinemia is seen in most of cases of acute abdomen and these is found to be clue to circulating endotoxins which may impair the excretion of bilirubin by bile canaliculi and also bacterial load overwhelms kupffer cells function and may cause hepatocyte dysfunction. This hyperbilirubinemia is self-limiting and no specific management is necessary. By 5 th to 7 th postoperative day serum bilirubin levels are coming to normal level.