Self-Management Program (Parqve) Improves Quality of Life in Severe Knee Osteoarthritis

Abstract

Objective: To evaluate the effects of the self-management program PARQVE in patients with severe knee osteoarthritis (KOA). Methods: Prospective randomized controlled clinical trial with 65 grade IV Kelgren & Lawrence (K&L) KOA patients who were allocated into groups: Control (CG) and Intervention (IG). Both groups received usual care. IG also participated in two days of multi-professional interventions about OA (causes and treatment) and received the program’s DVD and book. Standing X-rays were obtained at inclusion and Ahlback’s classification was registered. Western Ontario and McMaster Universities Index (WOMAC), Numerical Rating Scale (NRS), Lequesne, weight, and body mass index (BMI) were obtained at inclusion, and after 6, 12 and 24 months. Results: Groups were similar at baseline, despite higher WOMAC stiffness scores and a greater number of Ahlback’s grade 4 and 5 in the IG. Only the IG improved WOMAC and total functions (p<0.001) during the study period above 12%, but did not reach the minimal clinically important difference of 20%. Best results were in one year. Non-significant improvements were observed without changes in body composition (P>0.05). Conclusions: Patients with severe KOA have mild to moderate function and quality of life improvement due to self-management program (PARQVE). Level of Evidence I; Therapeutic Studies; Prospective Randomized Controlled Trial.

The OARSI Joint Effort Initiative: Priorities for osteoarthritis management program implementation and research 2024–2028

“…It has been encouraging to see work around the continued testing of new OA management programs [ [12] , [13] , [14] , [15] ], and with others in the design and piloting phase ( Table 1 ). The JEI sees ongoing development and adaption of OA management programs as a continuing priority, including the adaption of existing programs to suit different contexts, including for the needs of LMICs and lower-resourced settings.…”

“…Over the last 5 years, work by our members and wider networks have conducted studies that meet many of our priority research areas. Much of this work has been focused on implementing new models of care for OA management programs [ [12] , [13] , [14] , [15] ], many with a growing emphasis on using technology to improve program access [ [16] , [17] , [18] , [19] ]. Similarly, we have noted increased attention on evaluation and strengthening the delivery of existing programs [ [20] , [21] , [22] , [23] ], including studies that identify barriers and facilitators to implementation [ [24] , [25] , [26] ] or that are specific to local regions [ 12 , 27 , 28 ].…”